MedKoo Cat#: 524961 | Name: DIBA
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

DIBA is an ER zinc finger inhibitor that blocks ligand-dependent and -independent cell growth of TAM-resistant breast cancer in vitro and in vivo.

Chemical Structure

 DIBA
DIBA
CAS#171744-39-1

Theoretical Analysis

MedKoo Cat#: 524961

Name: DIBA

CAS#: 171744-39-1

Chemical Formula: C26H22N4O6S4

Exact Mass: 614.0422

Molecular Weight: 614.74

Elemental Analysis: C, 50.80; H, 3.61; N, 9.11; O, 15.62; S, 20.86

Price and Availability

Size Price Availability Quantity
5mg USD 350.00 Back order
25mg USD 850.00 Back order
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Related CAS #
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Synonym
DIBA; DIBA (Antineoplastic); DIBA-1; PD-22551; PD22551; PD 22551; PD022551; PD 022551; PD-022551; NSC 654077; NSC654077; NSC-654077;
IUPAC/Chemical Name
2,2'-Dithiobis-(N-(4-sulfamoylphenyl)-benzamide)
InChi Key
FVGJPHFQQMQGFQ-UHFFFAOYSA-N
InChi Code
InChI=1S/C26H22N4O6S4/c27-39(33,34)19-13-9-17(10-14-19)29-25(31)21-5-1-3-7-23(21)37-38-24-8-4-2-6-22(24)26(32)30-18-11-15-20(16-12-18)40(28,35)36/h1-16H,(H,29,31)(H,30,32)(H2,27,33,34)(H2,28,35,36)
SMILES Code
C1=CC=C(C(=C1)C(=O)NC2=CC=C(C=C2)S(=O)(=O)N)SSC3=CC=CC=C3C(=O)NC4=CC=C(C=C4)S(=O)(=O)N
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO, not in water
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 614.74 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Wang LH, Yang XY, Zhang X, An P, Kim HJ, Huang J, Clarke R, Osborne CK, Inman JK, Appella E, Farrar WL. Disruption of estrogen receptor DNA-binding domain and related intramolecular communication restores tamoxifen sensitivity in resistant breast cancer. Cancer Cell. 2006 Dec;10(6):487-99. PubMed PMID: 17157789.