MedKoo Cat#: 524480 | Name: BMS-480404

Description:

WARNING: This product is for research use only, not for human or veterinary use.

BMS-480404 is a potent small molecule inhibitor bound to human keratinocyte fatty acid-binding protein.

Chemical Structure

BMS-480404
BMS-480404
CAS#533889-36-0

Theoretical Analysis

MedKoo Cat#: 524480

Name: BMS-480404

CAS#: 533889-36-0

Chemical Formula: C22H18Cl2O5

Exact Mass: 432.0531

Molecular Weight: 433.28

Elemental Analysis: C, 60.98; H, 4.19; Cl, 16.36; O, 18.46

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
BMS-480404; BMS 480404; BMS480404; UNII-T78485CEYD.
IUPAC/Chemical Name
Benzeneacetic acid, 2,3-bis((2-chlorophenyl)methoxy)-alpha-hydroxy-, (alphaS)-
InChi Key
NCWQPARYSYJFNI-FQEVSTJZSA-N
InChi Code
InChI=1S/C22H18Cl2O5/c23-17-9-3-1-6-14(17)12-28-19-11-5-8-16(20(25)22(26)27)21(19)29-13-15-7-2-4-10-18(15)24/h1-11,20,25H,12-13H2,(H,26,27)/t20-/m0/s1
SMILES Code
c1ccc(c(c1)COc2cccc(c2OCc3ccccc3Cl)[C@@H](C(=O)O)O)Cl
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO, not in water
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 433.28 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: McDonnell PA, Constantine KL, Goldfarb V, Johnson SR, Sulsky R, Magnin DR, Robl JA, Caulfield TJ, Parker RA, Taylor DS, Adam LP, Metzler WJ, Mueller L, Farmer BT 2nd. NMR structure of a potent small molecule inhibitor bound to human keratinocyte fatty acid-binding protein. J Med Chem. 2006 Aug 10;49(16):5013-7. PubMed PMID: 16884313.