MedKoo Cat#: 407348 | Name: BMS-817378
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

BMS-817378, also known as SCR-1481B1 is a potent and selective MET inhibitor. SCR-1481B1 inhibited MET kinase with IC50 = 1.7 nM.

Chemical Structure

BMS-817378
BMS-817378
CAS#1174161-86-4 (tris)

Theoretical Analysis

MedKoo Cat#: 407348

Name: BMS-817378

CAS#: 1174161-86-4 (tris)

Chemical Formula: C31H35ClF2N5O10P

Exact Mass: 0.0000

Molecular Weight: 742.07

Elemental Analysis: C, 50.18; H, 4.75; Cl, 4.78; F, 5.12; N, 9.44; O, 21.56; P, 4.17

Price and Availability

Size Price Availability Quantity
50mg USD 450.00 2 Weeks
100mg USD 750.00 2 Weeks
200mg USD 1,250.00 2 Weeks
500mg USD 2,850.00 2 Weeks
1g USD 3,850.00 2 Weeks
2g USD 5,950.00 2 Weeks
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Related CAS #
1174161-86-4 (tris) 1174161-69-3 (free base)
Synonym
SCR-1481B1; SCR 1481B1; SCR1481B1; BMS-817378; BMS 817378; BMS817378;
IUPAC/Chemical Name
3-amino-3-(2-hydroxyethyl)pentane-1,5-diol (3-((4-((2-amino-3-chloropyridin-4-yl)oxy)-3-fluorophenyl)carbamoyl)-5-(4-fluorophenyl)-4-oxopyridin-1(4H)-yl)methyl phosphate
InChi Key
WKVFJHVNLKYURK-UHFFFAOYSA-N
InChi Code
InChI=1S/C24H18ClF2N4O7P.C7H17NO3/c25-21-20(7-8-29-23(21)28)38-19-6-5-15(9-18(19)27)30-24(33)17-11-31(12-37-39(34,35)36)10-16(22(17)32)13-1-3-14(26)4-2-13;8-7(1-4-9,2-5-10)3-6-11/h1-11H,12H2,(H2,28,29)(H,30,33)(H2,34,35,36);9-11H,1-6,8H2
SMILES Code
O=C(C1=CN(C=C(C1=O)C2=CC=C(C=C2)F)COP(O)(O)=O)NC3=CC=C(OC4=C(Cl)C(N)=NC=C4)C(F)=C3.NC(CCO)(CCO)CCO
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO, not in water
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 742.07 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL