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MedKoo Cat#: 318905 | Name: Tridihexethyl chloride

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Tridihexethyl is an anticholinergic, antimuscarinic and antispasmodic drug. It may be used, usually in combination with other drugs, to treat acquired nystagmus or peptic ulcer disease.

Chemical Structure

Tridihexethyl chloride
Tridihexethyl chloride
CAS#4310-35-4 (chloride)

Theoretical Analysis

MedKoo Cat#: 318905

Name: Tridihexethyl chloride

CAS#: 4310-35-4 (chloride)

Chemical Formula: C21H36ClNO

Exact Mass: 318.2791

Molecular Weight: 353.98

Elemental Analysis: C, 71.26; H, 10.25; Cl, 10.01; N, 3.96; O, 4.52

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
125-99-5 (iodide) 4310-35-4 (chloride) 60-49-1 (cation)
Synonym
Tridihexethyl, Pathilon, Propethonum; Tridihexethyl chloride.
IUPAC/Chemical Name
3-cyclohexyl-N,N,N-triethyl-3-hydroxy-3-phenylpropan-1-aminium chloride
InChi Key
XJGONMZLEDGBRM-UHFFFAOYSA-M
InChi Code
InChI=1S/C21H36NO.ClH/c1-4-22(5-2,6-3)18-17-21(23,19-13-9-7-10-14-19)20-15-11-8-12-16-20;/h7,9-10,13-14,20,23H,4-6,8,11-12,15-18H2,1-3H3;1H/q+1;/p-1
SMILES Code
OC(C1=CC=CC=C1)(C2CCCCC2)CC[N+](CC)(CC)CC.[Cl-]
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO, not in water
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 353.98 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Leigh RJ, Burnstine TH, Ruff RL, Kasmer RJ. Effect of anticholinergic agents upon acquired nystagmus: a double-blind study of trihexyphenidyl and tridihexethyl chloride. Neurology. 1991 Nov;41(11):1737-41. PubMed PMID: 1944902. 2: Kirchhoefer RD. Semiautomated determination of tridihexethyl chloride in meprobamate tablets. J Assoc Off Anal Chem. 1984 Jul-Aug;67(4):677-8. PubMed PMID: 6469893. 3: Lippold BC, Lettenbauer WA. [The absorption of homologous alkyl sulphonates of tridihexethyl (author's transl)]. Pharmazie. 1980;35(10):612-20. German. PubMed PMID: 6256779. 4: Lippold BC, Lettenbauer WA. [Membrane diffusion of homologous organic salts of tridihexethyl]. Pharmazie. 1978 Apr;33(4):221-5. German. PubMed PMID: 674319. 5: GARCIAHERRERA E, GARCIAHERRERA A. [TREATMENT OF GASTROINTESTINAL SPASM IN THE CHILD WITH A SOLUTION OF TRIDIHEXETHYL CHLORIDE]. Medicina (Mex). 1963 Oct 10;43:475-80. Spanish. PubMed PMID: 14107303. 6: PHILLIPS FJ. Peptic ulcer: treatment with a combination of meprobamate and tridihexethyl chloride. Clin Med (Northfield). 1963 Jul;70:1303-6. PubMed PMID: 15445911. 7: OSTERBERG AC, GRAY WD. The anticholinergic actions of tridihexethyl iodide. Arch Int Pharmacodyn Ther. 1962 Jun 1;137:250-66. PubMed PMID: 14482588. 8: SLATER S, NUMEROFF M. Effect of meprobamate-tridihexethyl iodide on the uptake of radioactive iodine and on the serum protein-bound iodine. N Engl J Med. 1958 Nov 13;259(20):974-5. PubMed PMID: 13600606.