Synonym
GYKI-23107; GYKI 23107; GYKI23107; GYKI-23,107; GYKI 23,107; GYKI23,107; GYKI-23107 HCl; GYKI-23107 hydrochloride
IUPAC/Chemical Name
N1-(2,6-dimethylphenyl)-N2,N2-dimethylpropane-1,2-diamine dihydrochloride
InChi Key
OILXHOMZZDEACA-UHFFFAOYSA-N
InChi Code
InChI=1S/C13H22N2.2ClH/c1-10-7-6-8-11(2)13(10)14-9-12(3)15(4)5;;/h6-8,12,14H,9H2,1-5H3;2*1H
SMILES Code
CC(N(C)C)CNC1=C(C)C=CC=C1C.[H]Cl.[H]Cl
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO, not in water
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
|
Solvent |
mg/mL |
mM |
comments |
| Solubility |
| Soluble in DMSO, not in water |
0.0 |
100.00 |
|
Note: There can be variations in solubility for the same chemical from different vendors or different batches from the same vendor. The following factors can affect the solubility of the same chemical: solvent used for crystallization, residual solvent content, polymorphism, salt versus free form, degree of hydration, solvent temperature. Please use the solubility data as a reference only. Warming and sonication will facilitate dissolving. Still have questions? Please contact our Technical Support scientists.
Preparing Stock Solutions
The following data is based on the
product
molecular weight
279.25
Batch specific molecular weights may vary
from batch to batch
due to the degree of hydration, which will
affect the solvent
volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass |
1 mg |
5 mg |
10 mg |
| 1 mM |
1.15 mL |
5.76 mL |
11.51 mL |
| 5 mM |
0.23 mL |
1.15 mL |
2.3 mL |
| 10 mM |
0.12 mL |
0.58 mL |
1.15 mL |
| 50 mM |
0.02 mL |
0.12 mL |
0.23 mL |
1: Varró A, Németh M, Rabloczky G, Papp JG, Szekeres L. Electrophysiological effects of GYKI-23 107, a new antiarrhythmic compound, in isolated rabbit and canine cardiac preparations. J Cardiovasc Pharmacol. 1988 Mar;11(3):251-7. PubMed PMID: 2452917.
2: Szatmary LJ, Rabloczky G, Kurthy M, Frater E, Solti F. Antifibrillatory effect of GYKI-23107 in induced ventricular vulnerability by local cooling and programmed stimulation in canine models. Acta Med Hung. 1988;45(2):221-9. PubMed PMID: 3247245.
3: Szatmary LJ, Rabloczky G, Kurthy M, Varro A, Solti F. Electrophysiological effects of the antiarrhythmic agent GYKI-23107 in dogs. Acta Med Hung. 1988;45(2):209-19. PubMed PMID: 3247244.
4: Varró A, Rabloczky G, Jaszlits L, Kürthy M, Zubovics Z, Toldy L. Pharmacological investigation of a new anti-arrhythmic agent, GYKI-23 107. Drugs Exp Clin Res. 1987;13(1):21-8. PubMed PMID: 3595441.
