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MedKoo Cat#: 318901 | Name: Triamcinolone
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

Triamcinolone is used to treat a number of different medical conditions, such as eczema, psoriasis, arthritis, allergies, ulcerative colitis, lupus, sympathetic ophthalmia, temporal arteritis, uveitis, ocular inflammation, Urushiol-induced contact dermatitis, aphthous ulcers (usually as triamcinolone acetonide), visualization during vitrectomy and the prevention of asthma attacks. It will not treat an asthma attack once it has already begun. It has also been used off-label for macular degeneration.

Chemical Structure

Triamcinolone
Triamcinolone
CAS#124-94-7 (free)

Theoretical Analysis

MedKoo Cat#: 318901

Name: Triamcinolone

CAS#: 124-94-7 (free)

Chemical Formula: C21H27FO6

Exact Mass: 394.1792

Molecular Weight: 394.44

Elemental Analysis: C, 63.95; H, 6.90; F, 4.82; O, 24.34

Price and Availability

Size Price Availability Quantity
100mg USD 150.00
200mg USD 250.00
500mg USD 450.00
1g USD 650.00
2g USD 1,050.00
5g USD 1,950.00 2 Weeks
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Related CAS #
124-94-7 (free) 76-25-5 (acetonide) 67-78-7 (diacetate) 5611-51-8 (hexacetonide)
Synonym
BRN-2341955; BRN2341955; BRN 2341955; Triamcinolone; Adcortyl; Aristocort
IUPAC/Chemical Name
(8S,9R,10S,11S,13S,14S,16R,17S)-9-fluoro-11,16,17-trihydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-3-one
InChi Key
GFNANZIMVAIWHM-OBYCQNJPSA-N
InChi Code
InChI=1S/C21H27FO6/c1-18-6-5-12(24)7-11(18)3-4-13-14-8-15(25)21(28,17(27)10-23)19(14,2)9-16(26)20(13,18)22/h5-7,13-16,23,25-26,28H,3-4,8-10H2,1-2H3/t13-,14-,15+,16-,18-,19-,20-,21-/m0/s1
SMILES Code
C[C@@]12[C@](C(CO)=O)(O)[C@H](O)C[C@@]1([H])[C@]3([H])CCC4=CC(C=C[C@]4(C)[C@@]3(F)[C@@H](O)C2)=O
Appearance
White to off-white crystalline powder.
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO, not in water
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 394.44 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
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Corticosteroid Injections for Frozen Shoulder: A Global Online Survey of Health Professionals' Current Practice and Opinion. Musculoskeletal Care. 2025 Mar;23(1):e70078. doi: 10.1002/msc.70078. PMID: 40139912; PMCID: PMC11946008. 6: Turgut MC, Şahbat Y, Afşar A, Turgut A, Engin MÇ, Akkaya GS. Comparing the clinical efficacy of multiple vs. single dose ozone (O2-O3) injections and corticosteroid injection in subacromial impingement syndrome: A prospective, randomized controlled trial with One-Year Follow-Up. J Back Musculoskelet Rehabil. 2025 Mar 25:10538127251322859. doi: 10.1177/10538127251322859. Epub ahead of print. PMID: 40129390. 7: Liu K, Yi J, Xu J, Zhong L, Su N. Risk of intraocular pressure elevation associated with triamcinolone acetonide administration via different routes in macular edema: a systematic review and network meta-analysis of randomized controlled trials. BMC Ophthalmol. 2025 Mar 25;25(1):150. doi: 10.1186/s12886-025-03979-z. PMID: 40128688; PMCID: PMC11934556. 8: Cardenas A, Martinez E, Nguyen K. Toxic Epidermal Necrolysis-Like Acute Cutaneous Lupus Erythematosus With Histiocytic Necrotizing Lymphadenitis: A Case Report. Cureus. 2025 Feb 19;17(2):e79275. doi: 10.7759/cureus.79275. PMID: 40125107; PMCID: PMC11926924. 9: Sahoo A, Paidesetty SK, Panda M. Target-specific high-throughput screening of anti-inflammatory phytosteroids for autoimmune diseases: A molecular docking- dynamics simulation approach. Steroids. 2025 Mar 20;217:109601. doi: 10.1016/j.steroids.2025.109601. Epub ahead of print. PMID: 40120839. 10: Chen J, Li B, Zuo S, Zhang K, Dai J, Chen L, Zhao Y. Pattern Recognition- Driven Detection of Circadian-Disruptive Compounds from Gene Expressions: High- Throughput Screening and Experimental Verification. Environ Sci Technol. 2025 Mar 22. doi: 10.1021/acs.est.4c12466. Epub ahead of print. PMID: 40120133. 11: Spitzer AI, Mont MA, Lin JH, Dasa V, Rivadeneyra A, Rogenmoser D, Concoff AL, Ng MK, DiGiorgi M, Dysart S, Urban J, Mihalko WM. Treatment Journey for Nonoperative Symptomatic Knee Osteoarthritis: Data from a New Real-World Registry. Surg Technol Int. 2025 Mar 21;45:sti45/1860. Epub ahead of print. PMID: 40117656. 12: Adriono GA, Triyoga IF, Kadharusman MM, Victor AA, Djatikusumo A, Yudantha AR, Hutapea MM. Efficacy and Safety of Ophthalmic Steroids in the Management of Polypoidal Choroidal Vasculopathy: A Systematic Review. Clin Ophthalmol. 2025 Mar 15;19:915-931. doi: 10.2147/OPTH.S517296. PMID: 40110363; PMCID: PMC11921791. 13: Jayadev S, Yusuff I, Shakeel F, Uthumansha U. Ultra-performance liquid chromatography method for quantitative analysis of nystatin and triamcinolone acetonide in topical creams after in vitro release using franz diffusion cell. BMC Chem. 2025 Mar 19;19(1):74. doi: 10.1186/s13065-025-01446-w. PMID: 40108652; PMCID: PMC11924836. 14: Cavada MN, Lee MF, Ananda A, Sacks R, Naidoo YS. Double-Blinded Randomised Controlled Trial Evaluating the Efficacy of Chitogel Versus PureRegen Gel on Postoperative Outcomes from Endoscopic Sinus Surgery. Am J Rhinol Allergy. 2025 Mar 19:19458924251321142. doi: 10.1177/19458924251321142. Epub ahead of print. PMID: 40105364. 15: Mont MA, Lin JH, Spitzer AI, Dasa V, Rivadeneyra A, Rogenmoser D, Concoff AL, Ng MK, DiGiorgi M, DySart S, Urban J, Mihalko WM. Improved Sleep Associated With Triamcinolone Acetonide Extended-Release Injections for Knee Osteoarthritis: Use of a New Real-World Registry. Arthroplast Today. 2025 Mar 1;32:101655. doi: 10.1016/j.artd.2025.101655. PMID: 40104775; PMCID: PMC11914753. 16: Güler E, Doğanci A. A new approach in the treatment of ultrasound-guided synovial hypertrophy. Turk J Med Sci. 2024 Nov 11;55(1):178-183. doi: 10.55730/1300-0144.5955. PMID: 40104292; PMCID: PMC11913489. 17: Ng K, Priyadarshini G, Sarker SJ, Robinson A, McPhail N, Prendergrast A, Ackermann C, Xhafa-Hamiti E, Greenwood M, Taylor N, Drake W, Shamash J. A Phase II, Single Arm, Multicentre Trial of Triamcinolone With a GnRH Analog for Castrate-Resistant Prostate Cancer (TRICREST). Prostate. 2025 Mar 18:e24877. doi: 10.1002/pros.24877. Epub ahead of print. PMID: 40103205. 18: Noh SH, Lee SW, Hwang JM, Jung J, Lee E, Cho DC, Kim CH, Kim KT. Intraoperative Facet Joint Block Reduces Pain After Oblique Lumbar Interbody Fusion: A Double-Blinded, Randomized, Placebo-Controlled Clinical Trial. J Bone Joint Surg Am. 2025 Jan 1;107(1):16-25. doi: 10.2106/JBJS.23.01480. Epub 2024 Nov 20. PMID: 40100010. 19: Rubio-Emazabel L, Polo Y, Ayerdi-Izquierdo A, Garcia-Urkia N, Álvarez-Luque N, Sarasua JR, Fernández J, Muñoz A. Biodegradable Poly(d,l-lactide-co-ε-caprolactone) Electrospun Scaffolds Outperform Antifibrotic-Loaded Meshes in an in Vivo Tissue Regeneration Model. ACS Appl Bio Mater. 2025 Mar 18. doi: 10.1021/acsabm.4c01715. Epub ahead of print. PMID: 40099893. 20: Zhu Q, Pan X, Du Z, Ying J, Hu Y, Yi Q, Fu X. From Monotherapy to Combination Strategies: Redefining Treatment Approaches for Multiple-Cause Macular Edema. Clin Ophthalmol. 2025 Mar 12;19:887-897. doi: 10.2147/OPTH.S513141. PMID: 40099235; PMCID: PMC11912219.