BPH-652 is a squalene synthase (SQS) inhibitor or dehydrosqualene synthase (CrtM) inhibitor. BPH-652 targets the biosynthesis of Staphyloxanthin (STX). The essential nature of STX is to act as a virulence factor with antioxidant properties; indeed, unpigmented microbes are more susceptible to host killing. Therefore, the intervention of STX biosynthesis may offer a new avenue to treat S. aureus or even MRSA infections.
MedKoo Cat#: 522687
Name: BPH-652 potassium
CAS#: 157124-84-0 (potassium)
Chemical Formula: C16H16K3O7PS
Exact Mass:
Molecular Weight: 500.63
Elemental Analysis: C, 38.39; H, 3.22; K, 23.43; O, 22.37; P, 6.19; S, 6.40
The following data is based on the product molecular weight 500.63 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
