CGP60474 is a potent dual cdk1/cdk2 inhibitor (IC50 values are 20 and 50 nM, respectively). Also displays low micromolar activity at PKCα. Displays reversible G1/S cell cycle arrest in U2-OS cells.
MedKoo Cat#: 523130
Name: CGP60474
CAS#: 164658-13-3
Chemical Formula: C18H18ClN5O
Exact Mass: 355.1200
Molecular Weight: 355.83
Elemental Analysis: C, 60.76; H, 5.10; Cl, 9.96; N, 19.68; O, 4.50
The following data is based on the product molecular weight 355.83 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
