Vacquinol-1 | NSC 13316 | CAS#5428-80-8 | MKK4-Dependent Macropinocytotic

MedKoo Cat#: 558277 | Name: Vacquinol-1

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Vacquinol-1, also known as NSC 13316, is an activator of MKK4-dependent macropinocytotic cell death in glioblastoma cells. Vacquinol-1 has beneficial effects on a glioblastoma multiforme mouse model by oral administration. In glioblastoma cells, Vacquinol-1 targets macropinocytosis, a cellular process that will not lead to cell death in normal cells.

Chemical Structure

Vacquinol-1

CAS#5428-80-8

Theoretical Analysis

MedKoo Cat#: 558277

Name: Vacquinol-1

CAS#: 5428-80-8

Chemical Formula: C21H21ClN2O

Exact Mass: 352.1342

Molecular Weight: 352.86

Elemental Analysis: C, 71.48; H, 6.00; Cl, 10.05; N, 7.94; O, 4.53

Price and Availability

Size	Price	Availability	Quantity
100mg	USD 1,250.00
200mg	USD 1,950.00
500mg	USD 2,650.00
1g	USD 3,250.00
2g	USD 4,950.00

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Related CAS #

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Synonym

NSC 13316; NSC-13316; NSC13316; Vacquinol-1

IUPAC/Chemical Name

(2-(4-chlorophenyl)quinolin-4-yl)(piperidin-2-yl)methanol

InChi Key

VKLJPGAHSLIQKH-UHFFFAOYSA-N

InChi Code

InChI=1S/C21H21ClN2O/c22-15-10-8-14(9-11-15)20-13-17(16-5-1-2-6-18(16)24-20)21(25)19-7-3-4-12-23-19/h1-2,5-6,8-11,13,19,21,23,25H,3-4,7,12H2

SMILES Code

ClC1=CC=C(C2=NC(C=CC=C3)=C3C(C(O)C4NCCCC4)=C2)C=C1

Appearance

White to beige solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO, not in water

Shelf Life

>2 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 352.86 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

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