Balapiravir | RO4588161 | CAS#690270-29-2 | polymerase inhibitor

MedKoo Cat#: 319850 | Name: Balapiravir

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Description:

WARNING: This product is for research use only, not for human or veterinary use.

Balapiravir, also known as R1626 and RO4588161, is a polymerase inhibitor and a tri-isobutyl ester prodrug of R1479, was developed to increase bioavailability and improve antiviral activity.

Chemical Structure

Balapiravir

CAS#690270-29-2 (free base)

Theoretical Analysis

MedKoo Cat#: 319850

Name: Balapiravir

CAS#: 690270-29-2 (free base)

Chemical Formula: C21H30N6O8

Exact Mass: 494.2125

Molecular Weight: 494.51

Elemental Analysis: C, 51.01; H, 6.12; N, 17.00; O, 25.88

Price and Availability

Size	Price	Availability
5mg	USD 450.00	2 Weeks
10mg	USD 800.00	2 Weeks
50mg	USD 2,250.00	2 Weeks

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Related CAS #

690270-29-2 (free base) 690270-65-6 (HCl)

Synonym

R1626; R-1626; R 1626; RO4588161; RO-4588161; RO 4588161; Balapiravir.

IUPAC/Chemical Name

(2R,3S,4R,5R)-5-(4-amino-2-oxopyrimidin-1(2H)-yl)-2-azido-2-((isobutyryloxy)methyl)tetrahydrofuran-3,4-diyl bis(2-methylpropanoate)

InChi Key

VKXWOLCNTHXCLF-DXEZIKHYSA-N

InChi Code

InChI=1S/C21H30N6O8/c1-10(2)17(28)32-9-21(25-26-23)15(34-19(30)12(5)6)14(33-18(29)11(3)4)16(35-21)27-8-7-13(22)24-20(27)31/h7-8,10-12,14-16H,9H2,1-6H3,(H2,22,24,31)/t14-,15+,16-,21-/m1/s1

SMILES Code

CC(C(O[C@H]([C@@H]([C@]1(COC(C(C)C)=O)N=[N+]=[N-])OC(C(C)C)=O)[C@@H](O1)N(C=CC(N)=N2)C2=O)=O)C

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO, not in water

Shelf Life

>2 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

	Solvent	mg/mL	mM
Solubility
	SDMSO	100.0	202.22

Note: There can be variations in solubility for the same chemical from different vendors or different batches from the same vendor. The following factors can affect the solubility of the same chemical: solvent used for crystallization, residual solvent content, polymorphism, salt versus free form, degree of hydration, solvent temperature. Please use the solubility data as a reference only. Warming and sonication will facilitate dissolving. Still have questions? Please contact our Technical Support scientists.

Preparing Stock Solutions

The following data is based on the product molecular weight 494.51 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

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