Fasitibant chloride, also known as MEN16132, is a potent and selective nonpeptide kinin B2 receptor antagonist. MEN16132 inhibited in a dose-dependent manner the bronchoconstriction induced by BK (10 nmol/kg i.v.). MEN16132 was more potent and possessed a longer duration of action as compared with the peptide B(2) receptor antagonist icatibant.
MedKoo Cat#: 319787
Name: Fasitibant chloride (HCl salt)
CAS#: 869880-33-1 (HCl salt)
Chemical Formula: C36H50Cl4N6O6S
Exact Mass: 0.0000
Molecular Weight: 836.69
Elemental Analysis: C, 51.68; H, 6.02; Cl, 16.95; N, 10.04; O, 11.47; S, 3.83
The following data is based on the product molecular weight 836.69 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
