Neomycin is an aminoglycoside antibiotic found in many topical medications such as creams, ointments, and eyedrops. Neomycin belongs to aminoglycoside class of antibiotics that contain two or more aminosugars connected by glycosidic bonds. Similar to other aminoglycosides, neomycin has excellent activity against Gram-negative bacteria, and has partial activity against Gram-positive bacteria. It is relatively toxic to humans, and many people have allergic reactions to it. Aminoglycosides such as neomycin are known for their ability to bind to duplex RNA with high affinity.
MedKoo Cat#: 319519
Name: Neomycin B sulfate
CAS#: 4146-30-9 (B sulfate)
Chemical Formula: C23H52N6O25S3
Exact Mass: 0.0000
Molecular Weight: 908.87
Elemental Analysis: C, 30.40; H, 5.77; N, 9.25; O, 44.01; S, 10.58
| Solvent | mg/mL | mM | |
|---|---|---|---|
| Solubility | |||
| Water | 175.0 | 192.55 |
The following data is based on the product molecular weight 908.87 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
