BRD73954 is a small molecule inhibitor that potently inhibits HDAC6 and HDAC8. It inhibits HDAC6, a class IIb histone that deacetylates cytoplasmic proteins, including tubulin, heat shock protein 90, and cortactin, and has roles in cell adhesion and motility. It is also an inhibitor of HDAC8, a class I histone that primarily targets nuclear proteins, including histones and cohesins, and regulates gene expression.
MedKoo Cat#: 522465
Name: BRD73954
CAS#: 1440209-96-0
Chemical Formula: C16H16N2O3
Exact Mass: 284.1161
Molecular Weight: 284.32
Elemental Analysis: C, 67.59; H, 5.67; N, 9.85; O, 16.88
The following data is based on the product molecular weight 284.32 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
