KAR675 | An antimalaria agent

MedKoo Cat#: 128990 | Name: KAR675

Description:

WARNING: This product is for research use only, not for human or veterinary use.

KAR675 is an antimalaria agent.

Chemical Structure

KAR675

CAS#N/A

Theoretical Analysis

MedKoo Cat#: 128990

Name: KAR675

CAS#: N/A

Chemical Formula: C23H31N3

Exact Mass: 349.2518

Molecular Weight: 349.52

Elemental Analysis: C, 79.04; H, 8.94; N, 12.02

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

Bulk Inquiry

Related CAS #

No Data

Synonym

KAR675; KAR 675; KAR-675

IUPAC/Chemical Name

(3s,5s,7s)-N-((Z)-(3',4'-diethyl-1H,5'H-[2,2'-bipyrrol]-5'-ylidene)methyl)adamantan-1-amine

InChi Key

OGZGEKMSRVGRJO-WFMKYZJSSA-N

InChi Code

InChI=1S/C23H31N3/c1-3-18-19(4-2)22(20-6-5-7-24-20)26-21(18)14-25-23-11-15-8-16(12-23)10-17(9-15)13-23/h5-7,14-17,24-25H,3-4,8-13H2,1-2H3/b21-14-/t15-,16+,17-,23?

SMILES Code

CCC(C(C1=CC=CN1)=N/2)=C(CC)C2=C\NC3(C[C@@H]4C5)C[C@H](C4)C[C@H]5C3

Appearance

To be determined

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 -4 C for short term (days to weeks) or -20 C for long term(months to years).

Solubility

To be determined

Shelf Life

>2 years if stored properly

Drug Formulation

To be determined

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 349.52 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

Optimization of Tambjamines Active against Multiple Stages of Malaria Parasites Amrendra Kumar, Yuexin Li, Xiaowei Zhang, Xiannu Jin, William E. Dennis, Ravi Chetree, Cameron Blount, Diana Caridha, Michael S. Madejczyk, Patricia J. Lee, Kristina Pannone, Jesse DeLuca, Chau Vuong, Susan Leed, Hieu T. Dinh, Kennedy Mdaki, Rohit Mahato, Priyam Sen, Trisha Mondal, Karabi Phukan, Ankur Saha, Anongruk Chim-Ong, Liwang Cui, Rajachandrasekhar Valmon, Sivanna Chithanna, Rozalia A. Dodean, David H. Peyton, Stephen Orena, Jackson Assimwe, Innocent Tibagambirwa, Patrick Angutoko, Jennifer Legac, Oriana Kreutzfeld, Philip J. Rosenthal, Elodie Chenu, James Duffy, Alison Roth, Kevin A. Reynolds, Jane X. Kelly, and Papireddy Kancharla Journal of Medicinal Chemistry Article ASAP DOI: 10.1021/acs.jmedchem.5c00597