MedKoo Cat#: 128828 | Name: RS47
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

RS47 is a potent and specific inhibitor of the non-canonical NF-κB signaling pathway through disrupting RelB binding to its target DNA with a Kd values of 1.1 μM.

Chemical Structure

RS47
RS47
CAS#301655-16-3

Theoretical Analysis

MedKoo Cat#: 128828

Name: RS47

CAS#: 301655-16-3

Chemical Formula: C18H18N4O2S

Exact Mass: 354.1150

Molecular Weight: 354.43

Elemental Analysis: C, 61.00; H, 5.12; N, 15.81; O, 9.03; S, 9.05

Price and Availability

Size Price Availability Quantity
5mg USD 550.00 2 Weeks
25mg USD 950.00 2 Weeks
100mg USD 1,750.00 2 Weeks
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Related CAS #
No Data
Synonym
RS47; RS 47; RS-47
IUPAC/Chemical Name
(E)-2-(1-(2-(5,6,7,8-tetrahydrobenzo[4,5]thieno[2,3-d]pyrimidin-4-yl)hydrazineylidene)ethyl)benzene-1,4-diol
InChi Key
IMZXEXALIANGGH-UFFVCSGVSA-N
InChi Code
InChI=1S/C18H18N4O2S/c1-10(13-8-11(23)6-7-14(13)24)21-22-17-16-12-4-2-3-5-15(12)25-18(16)20-9-19-17/h6-9,23-24H,2-5H2,1H3,(H,19,20,22)/b21-10+
SMILES Code
C/C(C1=C(O)C=CC(O)=C1)=N\NC2=C(C3=C(S4)CCCC3)C4=NC=N2
Appearance
To be determined
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 -4 C for short term (days to weeks) or -20 C for long term(months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 354.43 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Pelling H, Bock LJ, Nzakizwanayo J, Wand ME, Denham EL, MacFarlane WM, Sutton JM, Jones BV. De-repression of the smvA efflux system arises in clinical isolates of Proteus mirabilis and reduces susceptibility to chlorhexidine and other biocides. Antimicrob Agents Chemother. 2019 Sep 9;63(12):e01535-19. doi: 10.1128/AAC.01535-19. Epub 2019 Sep 30. PMID: 31570392; PMCID: PMC6879213.