MedKoo Cat#: 571633 | Name: DSS-d4 Deuterated Crosslinker
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

DSS-d4 Deuterated Crosslinker, or Bis[Succinimidyl] 2,2,7,7-suberate-d4 is a cell membrane permeable crosslinking agent with 4 deuterium atoms that provide a 4 dalton shift by mass spectrometry analysis.

Chemical Structure

DSS-d4 Deuterated Crosslinker
DSS-d4 Deuterated Crosslinker
CAS#NONE

Theoretical Analysis

MedKoo Cat#: 571633

Name: DSS-d4 Deuterated Crosslinker

CAS#: NONE

Chemical Formula: C16H16D4N2O8

Exact Mass: 372.1471

Molecular Weight: 372.37

Elemental Analysis: C, 51.61; H, 6.49; N, 7.52; O, 34.37

Price and Availability

Size Price Availability Quantity
10mg USD 350.00 2 Weeks
50mg USD 1,050.00 2 Weeks
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Related CAS #
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Synonym
DSS-d4 Deuterated Crosslinker; DSS-d4; DSS Crosslinker-d4; Deuterated Crosslinker DSS-d4
IUPAC/Chemical Name
Suberic acid-2,2,7,7-d4 bis (N-hydroxysuccinimide ester)
InChi Key
ZWIBGKZDAWNIFC-NZLXMSDQSA-N
InChi Code
InChI=1S/C16H20N2O8/c19-11-7-8-12(20)17(11)25-15(23)5-3-1-2-4-6-16(24)26-18-13(21)9-10-14(18)22/h1-10H2/i5D2,6D2
SMILES Code
O=C(ON1C(CCC1=O)=O)C([2H])([2H])CCCCC([2H])([2H])C(ON2C(CCC2=O)=O)=O
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info
Use heavy DSS-d4 crosslinker in combination with DSS crosslinking reagent (the light, non-deuterated analog, DSS-d0) for mass spec studies.

Preparing Stock Solutions

The following data is based on the product molecular weight 372.37 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Haladová K, Mrázek H, Ječmen T, Halada P, Man P, Novák P, Chmelík J, Obšil T, Šulc M. The combination of hydrogen/deuterium exchange or chemical cross-linking techniques with mass spectrometry: mapping of human 14-3-3ζ homodimer interface. J Struct Biol. 2012 Jul;179(1):10-7. doi: 10.1016/j.jsb.2012.04.016. Epub 2012 May 2. PubMed PMID: 22580067.