MedKoo Cat#: 128777 | Name: EU1622-14

Description:

WARNING: This product is for research use only, not for human or veterinary use.

EU-1622-14 is a NMDAR PAM.

Chemical Structure

EU1622-14
EU1622-14
CAS#N/A

Theoretical Analysis

MedKoo Cat#: 128777

Name: EU1622-14

CAS#: N/A

Chemical Formula: C19H18BrN3O2S

Exact Mass: 431.0303

Molecular Weight: 432.34

Elemental Analysis: C, 52.79; H, 4.20; Br, 18.48; N, 9.72; O, 7.40; S, 7.42

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
EU-1622-14; EU 1622-14; EU1622-14
IUPAC/Chemical Name
5-(3-bromophenyl)-6-methyl-3-(2-oxo-2-(pyrrolidin-1-yl)ethyl)thieno[2,3-d]pyrimidin-4(3H)-one
InChi Key
QPGKZQJWYRRBQF-UHFFFAOYSA-N
InChi Code
InChI=1S/C19H18BrN3O2S/c1-12-16(13-5-4-6-14(20)9-13)17-18(26-12)21-11-23(19(17)25)10-15(24)22-7-2-3-8-22/h4-6,9,11H,2-3,7-8,10H2,1H3
SMILES Code
BrC1=CC=CC(C2=C(C)SC3=C2C(N(CC(N4CCCC4)=O)C=N3)=O)=C1
Appearance
To be determined
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 -4 C for short term (days to weeks) or -20 C for long term(months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 432.34 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Fritzemeier RG, Akins NS, Arcoria PJ, Paladugu S, Ullman EZ, Allen J, Sheikh R, Nocilla KA, McDaniels ED, Coleman EM, Antonoudiou P, D'Erasmo MP, Bartsch P, Sharma SK, Maguire J, Traynelis SF, Liotta DC. Thienopyrimidinone Derivatives as a GluN2B/C/D Biased, Positive Allosteric Modulator of the N-Methyl-d-Aspartate Receptor. J Med Chem. 2025 Apr 20. doi: 10.1021/acs.jmedchem.4c02912. Epub ahead of print. PMID: 40254917.