Versicolorone | CAS#84062-31-7 | biochemical

MedKoo Cat#: 146098 | Name: Versicolorone

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Versicolorone is a bioactive compound isolated from Ganoderma versicolor, a medicinal mushroom known for its therapeutic properties. It has demonstrated promising applications in traditional medicine, particularly for its anticancer, antioxidant, and anti-inflammatory effects. The mechanism of action of versicolorone involves the inhibition of key signaling pathways, including the NF-κB and MAPK pathways, which play roles in inflammation and cell proliferation. By modulating these pathways, versicolorone helps reduce inflammation and suppress tumor growth, making it a potential candidate for cancer therapy and other inflammatory diseases.

Chemical Structure

Versicolorone

CAS#84062-31-7

Theoretical Analysis

MedKoo Cat#: 146098

Name: Versicolorone

CAS#: 84062-31-7

Chemical Formula: C20H16O7

Exact Mass: 368.0896

Molecular Weight: 368.34

Elemental Analysis: C, 65.22; H, 4.38; O, 30.40

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

Bulk Inquiry

Related CAS #

No Data

Synonym

Versicolorone;

IUPAC/Chemical Name

4,6,8-trihydroxy-3-(3-oxobutyl)-2,3-dihydroanthra[2,3-b]furan-5,10-dione

InChi Key

XDLBESHDJXFECS-UHFFFAOYSA-N

InChi Code

1S/C20H16O7/c1-8(21)2-3-9-7-27-14-6-12-17(19(25)15(9)14)20(26)16-11(18(12)24)4-10(22)5-13(16)23/h4-6,9,22-23,25H,2-3,7H2,1H3

SMILES Code

CC(=O)CCC1COC2=C1C(O)=C3C(=O)C4=C(C=C(O)C=C4O)C(=O)C3=C2

Appearance

To be determined

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 -4 C for short term (days to weeks) or -20 C for long term(months to years).

Solubility

To be determined

Shelf Life

>2 years if stored properly

Drug Formulation

To be determined

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 368.34 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Tolmie C, Smit MS, Opperman DJ. Alternative Splicing of the Aflatoxin- Associated Baeyer⁻Villiger Monooxygenase from Aspergillus flavus: Characterisation of MoxY Isoforms. Toxins (Basel). 2018 Dec 5;10(12):521. doi: 10.3390/toxins10120521. PMID: 30563144; PMCID: PMC6315744. 2: Wen Y, Hatabayashi H, Arai H, Kitamoto HK, Yabe K. Function of the cypX and moxY genes in aflatoxin biosynthesis in Aspergillus parasiticus. Appl Environ Microbiol. 2005 Jun;71(6):3192-8. doi: 10.1128/AEM.71.6.3192-3198.2005. PMID: 15933021; PMCID: PMC1151844. 3: Yabe K, Chihaya N, Hamamatsu S, Sakuno E, Hamasaki T, Nakajima H, Bennett JW. Enzymatic conversion of averufin to hydroxyversicolorone and elucidation of a novel metabolic grid involved in aflatoxin biosynthesis. Appl Environ Microbiol. 2003 Jan;69(1):66-73. doi: 10.1128/AEM.69.1.66-73.2003. PMID: 12513978; PMCID: PMC152417. 4: Hodges RL, Kelkar HS, Xuei X, Skatrud PL, Keller NP, Adams TH, Kaiser RE, Vinci VA, McGilvray D. Characterization of an echinocandin B-producing strain blocked for sterigmatocystin biosynthesis reveals a translocation in the stcW gene of the aflatoxin biosynthetic pathway. J Ind Microbiol Biotechnol. 2000 Dec;25(6):333-341. doi: 10.1038/sj.jim.7000076. PMID: 11320421. 5: Shima Y, Shiina M, Shinozawa T, Ito Y, Nakajima H, Adachi Y, Yabe K. Participation in aflatoxin biosynthesis by a reductase enzyme encoded by vrdA gene outside the aflatoxin gene cluster. Fungal Genet Biol. 2009 Mar;46(3):221-31. doi: 10.1016/j.fgb.2008.12.005. Epub 2009 Jan 3. PMID: 19211038.