Ulimorelin hydrochloride monohydrate | CAS#951326-02-6 | GHS receptor agonist

MedKoo Cat#: 126238 | Name: Ulimorelin hydrochloride monohydrate

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Ulimorelin, also known as TZP-101, is a GHS receptor agonist potentially for the treatment of postoperative ileus and gastrointestinal disorders. TZP-101 accelerates gastric emptying in adults with diabetes and symptomatic gastroparesis. TZP-101 relieves gastroparesis associated with severe nausea and vomiting. TZP-101/ulimorelin accelerates gastrointestinal recovery independently of opioid use and surgery type.

Chemical Structure

Ulimorelin hydrochloride monohydrate

CAS#951326-02-6 (H2O)

Theoretical Analysis

MedKoo Cat#: 126238

Name: Ulimorelin hydrochloride monohydrate

CAS#: 951326-02-6 (H2O)

Chemical Formula: C30H42ClFN4O5

Exact Mass: 592.2828

Molecular Weight: 593.14

Elemental Analysis: C, 60.75; H, 7.14; Cl, 5.98; F, 3.20; N, 9.45; O, 13.49

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

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Related CAS #

842131-33-3 (free base) 874336-43-3 (HCl) 951326-02-6 (H2O)

Synonym

ULIMORELIN HYDROCHLORIDE; Ulimorelin hydrochloride monohydrate; Ulimorelin; TZP-101; TZP 101; TZP101

IUPAC/Chemical Name

(2R,5S,8R,11R)-5-cyclopropyl-11-(4-fluorobenzyl)-2,7,8-trimethyl-4,5,7,8,10,11,13,14,15,16-decahydro-2H-benzo[q][1]oxa[4,7,10,13]tetraazacyclooctadecine-6,9,12(3H)-trione hydrochloride hydrate

InChi Key

ZWIXEQBDJMFCMN-DHHNQDMHSA-N

InChi Code

InChI=1S/C30H39FN4O4.ClH.H2O/c1-19-18-33-27(23-12-13-23)30(38)35(3)20(2)28(36)34-25(17-21-10-14-24(31)15-11-21)29(37)32-16-6-8-22-7-4-5-9-26(22)39-19;;/h4-5,7,9-11,14-15,19-20,23,25,27,33H,6,8,12-13,16-18H2,1-3H3,(H,32,37)(H,34,36);1H;1H2/t19-,20-,25-,27+;;/m1../s1

SMILES Code

O.Cl.C[C@@H]1CN[C@@H](C2CC2)C(=O)N(C)[C@H](C)C(=O)N[C@H](CC3=CC=C(F)C=C3)C(=O)NCCCC4=C(O1)C=CC=C4

Appearance

To be determined

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 -4 C for short term (days to weeks) or -20 C for long term(months to years).

Solubility

To be determined

Shelf Life

>2 years if stored properly

Drug Formulation

To be determined

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 593.14 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

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