Dichloropane | CAS#146725-34-0 | biochemical

MedKoo Cat#: 146085 | Name: Dichloropane

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Dichloropane is a synthetic stimulant compound that is structurally related to the class of drugs known as cathinones, which are derivatives of the natural stimulant cathinone. It has been explored primarily in research contexts for its potential to affect the central nervous system. The mechanism of dichloropane involves inhibiting the reuptake of key neurotransmitters such as dopamine, serotonin, and norepinephrine, thereby increasing their levels in the brain and resulting in stimulating effects like enhanced alertness and euphoria.

Chemical Structure

Dichloropane

CAS#146725-34-0

Theoretical Analysis

MedKoo Cat#: 146085

Name: Dichloropane

CAS#: 146725-34-0

Chemical Formula: C15H17Cl2NO2

Exact Mass: 313.0636

Molecular Weight: 314.21

Elemental Analysis: C, 57.34; H, 5.45; Cl, 22.56; N, 4.46; O, 10.18

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

Bulk Inquiry

Related CAS #

No Data

Synonym

Dichloropane; O-456; O456; O 456;

IUPAC/Chemical Name

methyl (1R,2S,3S,5S)-3-(3,4-dichlorophenyl)-8-azabicyclo[3.2.1]octane-2-carboxylate

InChi Key

JFUNLJPTPCQLIR-PJQZNRQZSA-N

InChi Code

1S/C15H17Cl2NO2/c1-20-15(19)14-10(7-9-3-5-13(14)18-9)8-2-4-11(16)12(17)6-8/h2,4,6,9-10,13-14,18H,3,5,7H2,1H3/t9-,10+,13+,14-/m0/s1

SMILES Code

COC(=O)[C@@H]1[C@H]2CC[C@@H](C[C@@H]1C3=CC(Cl)=C(Cl)C=C3)N2

Appearance

To be determined

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 -4 C for short term (days to weeks) or -20 C for long term(months to years).

Solubility

To be determined

Shelf Life

>2 years if stored properly

Drug Formulation

To be determined

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 314.21 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Sorribes-Soriano A, Monedero A, Esteve-Turrillas FA, Armenta S. Determination of the new psychoactive substance dichloropane in saliva by microextraction by packed sorbent - Ion mobility spectrometry. J Chromatogr A. 2019 Oct 11;1603:61-66. doi: 10.1016/j.chroma.2019.06.054. Epub 2019 Jun 26. PMID: 31262514. 2: Fiala T, Wang J, Dunn M, Šebej P, Choi SJ, Nwadibia EC, Fialova E, Martinez DM, Cheetham CE, Fogle KJ, Palladino MJ, Freyberg Z, Sulzer D, Sames D. Chemical Targeting of Voltage Sensitive Dyes to Specific Cells and Molecules in the Brain. J Am Chem Soc. 2020 May 20;142(20):9285-9301. doi: 10.1021/jacs.0c00861. Epub 2020 May 12. PMID: 32395989; PMCID: PMC7750015. 3: Brownell AL, Elmaleh DR, Meltzer PC, Shoup TM, Brownell GL, Fischman AJ, Madras BK. Cocaine congeners as PET imaging probes for dopamine terminals. J Nucl Med. 1996 Jul;37(7):1186-92. PMID: 8965196. 4: Ishii K, Sasaki M, Kitagaki H, Sakamoto S, Yamaji S, Maeda K. Regional difference in cerebral blood flow and oxidative metabolism in human cortex. J Nucl Med. 1996 Jul;37(7):1086-8. PMID: 8965174.