MedKoo Cat#: 128622 | Name: Clozapine N-oxide 2HCl
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

Clozapine N-oxide dihydrochloride is a major metabolite of Clozapine and a human muscarinic designer receptors (DREADDs) agonist.

Chemical Structure

Clozapine N-oxide 2HCl
Clozapine N-oxide 2HCl
CAS#2250025-93-3 (2HCl)

Theoretical Analysis

MedKoo Cat#: 128622

Name: Clozapine N-oxide 2HCl

CAS#: 2250025-93-3 (2HCl)

Chemical Formula: C18H21Cl3N4O

Exact Mass: 414.0781

Molecular Weight: 415.74

Elemental Analysis: C, 52.00; H, 5.09; Cl, 25.58; N, 13.48; O, 3.85

Price and Availability

Size Price Availability Quantity
5mg USD 450.00 2 Weeks
25mg USD 950.00 2 Weeks
100mg USD 1,650.00 2 Weeks
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Synonym
Clozapine N-oxide dihydrochloride; Clozapine N-oxide 2HCl; Clozapine N-oxide; CNO
IUPAC/Chemical Name
4-(8-chloro-5H-dibenzo[b,e][1,4]diazepin-11-yl)-1-methylpiperazine 1-oxide dihydrochloride
InChi Key
MBRGKRXDVKTUPT-UHFFFAOYSA-N
InChi Code
InChI=1S/C18H19ClN4O.2ClH/c1-23(24)10-8-22(9-11-23)18-14-4-2-3-5-15(14)20-16-7-6-13(19)12-17(16)21-18;;/h2-7,12,20H,8-11H2,1H3;2*1H
SMILES Code
C[N+]1([O-])CCN(C2=NC3=CC(Cl)=CC=C3NC4=CC=CC=C42)CC1.[H]Cl.[H]Cl
Appearance
To be determined
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 -4 C for short term (days to weeks) or -20 C for long term(months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 415.74 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL