Synonym
Leucoquinizarin; NSC 42299; NSC-42299; NSC42299;
IUPAC/Chemical Name
1,4-dihydroxy-2,3-dihydroanthracene-9,10-dione
InChi Key
XVGQSHVTYJLKSM-UHFFFAOYSA-N
InChi Code
InChI=1S/C14H10O4/c15-9-5-6-10(16)12-11(9)13(17)7-3-1-2-4-8(7)14(12)18/h1-4,15-16H,5-6H2
SMILES Code
O=C(C1=C2C=CC=C1)C3=C(O)CCC(O)=C3C2=O
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.03.00
Preparing Stock Solutions
The following data is based on the
product
molecular weight
242.23
Batch specific molecular weights may vary
from batch to batch
due to the degree of hydration, which will
affect the solvent
volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass |
1 mg |
5 mg |
10 mg |
| 1 mM |
1.15 mL |
5.76 mL |
11.51 mL |
| 5 mM |
0.23 mL |
1.15 mL |
2.3 mL |
| 10 mM |
0.12 mL |
0.58 mL |
1.15 mL |
| 50 mM |
0.02 mL |
0.12 mL |
0.23 mL |
1: Bello López MA, Callejón Mochón M, Gómez Ariza JL, Guiraúm Pérez A. Leucoquinizarin as an analytical spectrophotometric and fluorimetric reagent: application to the determination of magnesium in pharmaceutical preparations. Analyst. 1986 Apr;111(4):429-33. PubMed PMID: 3717589.
2: Zee-Cheng RK, Cheng CC. Antineoplastic agents. Structure-activity relationship study of bis(substituted aminoalkylamino)anthraquinones. J Med Chem. 1978 Mar;21(3):291-4. PubMed PMID: 628005.
3: Dufat-Trinh Van H, Seguin E, Tillequin F, Monneret C, Koch M. [Total synthesis of oxa-9-anthracyclines]. Chem Pharm Bull (Tokyo). 1989 Dec;37(12):3294-300. French. PubMed PMID: 2632074.
4: Churchill MR, Keil KM, Bright FV, Pandey S, Baker GA, Keister JB. Linkage and redox isomerism in ruthenium complexes of catecholate, semiquinone, and o-acylphenolate ligands derived from 1,2-dihydroxy-9,10-anthracenedione (alizarin) and related species: syntheses, characterizations, and photophysics. Inorg Chem. 2000 Dec 11;39(25):5807-16. PubMed PMID: 11151384.
5: Giles GI, Sharma RP. Solid phase synthesis of anthraquinone peptides and their evaluation as topoisomerase I inhibitors. J Pept Sci. 2005 Jul;11(7):417-23. PubMed PMID: 15641118.
