(3R,4S)-Tofacitinib is a less active enantiomer of Tofacitinib and a first-in-class inhibitor of JAK3 with an IC50 of 1 nM.
MedKoo Cat#: 128585
Name: (3R,4S)-Tofacitinib
CAS#: 1092578-46-5
Chemical Formula: C16H20N6O
Exact Mass: 312.1699
Molecular Weight: 312.38
Elemental Analysis: C, 61.52; H, 6.45; N, 26.90; O, 5.12
The following data is based on the product molecular weight 312.38 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
