Acetylvardenafil is a synthetic derivative of vardenafil, a phosphodiesterase type 5 (PDE5) inhibitor, primarily used in the treatment of erectile dysfunction. It works by inhibiting the PDE5 enzyme, leading to increased levels of cyclic guanosine monophosphate (cGMP) in smooth muscle cells, which promotes vasodilation and enhances blood flow to the penis. This mechanism helps to improve erectile function by facilitating better blood circulation. Acetylvardenafil is also being investigated for its potential use in other vascular-related conditions and may have applications in treating pulmonary arterial hypertension.
MedKoo Cat#: 145988
Name: Acetylvardenafil
CAS#: 1261351-28-3
Chemical Formula: C25H34N6O3
Exact Mass: 466.2700
Molecular Weight: 466.59
Elemental Analysis: C, 64.36; H, 7.35; N, 18.01; O, 10.29
The following data is based on the product molecular weight 466.59 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
