OPC-3952 is a selective and potent inhibitor of the enzyme norepinephrine transporter (NET), which plays a crucial role in the reuptake of norepinephrine in the brain and peripheral nervous system. By inhibiting NET, OPC-3952 increases the levels of norepinephrine in synaptic clefts, which can help improve symptoms associated with conditions like attention-deficit hyperactivity disorder (ADHD) and depression. Its mechanism involves the modulation of norepinephrine signaling, enhancing neurotransmission and potentially improving mood, focus, and cognitive function. OPC-3952 is being explored as a therapeutic agent for psychiatric and neurological disorders where norepinephrine dysregulation is implicated.
MedKoo Cat#: 145980
Name: OPC-3952
CAS#: 62969-59-9
Chemical Formula: C22H29N5O4S
Exact Mass: 459.1900
Molecular Weight: 459.57
Elemental Analysis: C, 57.50; H, 6.36; N, 15.24; O, 13.93; S, 6.98
The following data is based on the product molecular weight 459.57 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
