Merulidial | CAS#68053-32-7 | sesquiterpene

MedKoo Cat#: 145828 | Name: Merulidial

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Merulidial is considered a sesquiterpene. Merulidial has been studied for its potential as an antibiotic

Chemical Structure

Merulidial

CAS#68053-32-7

Theoretical Analysis

MedKoo Cat#: 145828

Name: Merulidial

CAS#: 68053-32-7

Chemical Formula: C15H20O3

Exact Mass: 248.1400

Molecular Weight: 248.32

Elemental Analysis: C, 72.55; H, 8.12; O, 19.33

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

Bulk Inquiry

Related CAS #

No Data

Synonym

Merulidial;

IUPAC/Chemical Name

(1aR,5aR,6S,6aR)-6-hydroxy-4,4,6a-trimethyl-3,4,5,5a,6,6a-hexahydrocyclopropa[f]indene-1a,2(1H)-dicarbaldehyde

InChi Key

NFLNZGQBGCPDMT-WCUVEOEZSA-N

InChi Code

1S/C15H20O3/c1-13(2)4-9-10(5-13)12(18)14(3)7-15(14,8-17)11(9)6-16/h6,8,10,12,18H,4-5,7H2,1-3H3/t10-,12+,14+,15+/m1/s1

SMILES Code

[H][C@@]12CC(C)(C)CC1=C(C=O)[C@]3(C[C@@]3(C)[C@H]2O)C=O

Appearance

To be determined

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 -4 C for short term (days to weeks) or -20 C for long term(months to years).

Solubility

To be determined

Shelf Life

>2 years if stored properly

Drug Formulation

To be determined

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 248.32 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Quack W, Anke T, Oberwinkler F, Giannetti BM, Steglich W. Antibiotics from Basidiomycetes. V merulidial, a new antibiotic from the Basidiomycete Merulius tremellosus Fr. J Antibiot (Tokyo). 1978 Aug;31(8):737-41. doi: 10.7164/antibiotics.31.737. PMID: 567638. 2: Jonassohn M, Anke H, Morales P, Sterner O. Structure-activity relationships for unsaturated dialdehydes. 10. The generation of bioactive products by autoxidation of isovelleral and merulidial. Acta Chem Scand (Cph). 1995 Jul;49(7):530-5. doi: 10.3891/acta.chem.scand.49-0530. PMID: 7619631. 3: Anke H, Sterner O, Steglich W. Structure-activity relationships for unsaturated dialdehydes. 3. Mutagenic, antimicrobial, cytotoxic, and phytotoxic activities of merulidial derivatives. J Antibiot (Tokyo). 1989 May;42(5):738-44. doi: 10.7164/antibiotics.42.738. PMID: 2722688. 4: Svensson M, Lundgren LN, Woods C, Fatehi J, Stenlid J. Pyrone and pyridone compounds in the liquid culture of Physisporinus sanguinolentus. Phytochemistry. 2001 Apr;56(7):747-51. doi: 10.1016/s0031-9422(00)00414-3. PMID: 11314963. 5: Forsby A, Walum E, Sterner O. The effect of six sesquiterpenoid unsaturated dialdehydes on cell membrane permeability in human neuroblastoma SH-SY5Y cells. Chem Biol Interact. 1992 Sep 14;84(1):85-95. doi: 10.1016/0009-2797(92)90123-3. Erratum in: Chem Biol Interact 1993 Feb;86(2):183. PMID: 1394618.