MedKoo Cat#: 145805 | Name: AVE-9423

Description:

WARNING: This product is for research use only, not for human or veterinary use.

AVE-9423 is an experimental compound that has been studied for its potential use in the treatment of neurodegenerative diseases. It is part of a class of compounds that may target specific pathways involved in inflammation and neuroprotection. AVE-9423 has been researched for its effects on the central nervous system, with a focus on conditions like Alzheimer's disease and other forms of cognitive decline.

Chemical Structure

AVE-9423
AVE-9423
CAS#862243-29-6

Theoretical Analysis

MedKoo Cat#: 145805

Name: AVE-9423

CAS#: 862243-29-6

Chemical Formula: C23H12Cl2F2N2O5

Exact Mass: 504.0100

Molecular Weight: 505.25

Elemental Analysis: C, 54.68; H, 2.39; Cl, 14.03; F, 7.52; N, 5.54; O, 15.83

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
AVE-9423; AVE9423; AVE 9423;
IUPAC/Chemical Name
1-(2-carboxyphenyl)-7-chloro-6-((2-chloro-4,6-difluorophenyl)amino)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid
InChi Key
OEMJXSVJXPIFMA-UHFFFAOYSA-N
InChi Code
1S/C23H12Cl2F2N2O5/c24-14-8-19-12(7-17(14)28-20-15(25)5-10(26)6-16(20)27)21(30)13(23(33)34)9-29(19)18-4-2-1-3-11(18)22(31)32/h1-9,28H,(H,31,32)(H,33,34)
SMILES Code
OC(=O)C1=CC=CC=C1N2C=C(C(O)=O)C(=O)C3=C2C=C(Cl)C(NC4=C(F)C=C(F)C=C4Cl)=C3
Appearance
To be determined
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 -4 C for short term (days to weeks) or -20 C for long term(months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 505.25 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Anderka O, Loenze P, Klabunde T, Dreyer MK, Defossa E, Wendt KU, Schmoll D. Thermodynamic characterization of allosteric glycogen phosphorylase inhibitors. Biochemistry. 2008 Apr 22;47(16):4683-91. doi: 10.1021/bi702397d. Epub 2008 Mar 29. PMID: 18373353.