Synonym
Bullatenone; Bulatenone;
IUPAC/Chemical Name
2,2-dimethyl-5-phenylfuran-3(2H)-one
InChi Key
LTRTYBNTZIFLOT-UHFFFAOYSA-N
InChi Code
1S/C12H12O2/c1-12(2)11(13)8-10(14-12)9-6-4-3-5-7-9/h3-8H,1-2H3
SMILES Code
CC1(C)OC(=CC1=O)C2=CC=CC=C2
Appearance
To be determined
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 -4 C for short term (days to weeks) or -20 C for long term(months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
Preparing Stock Solutions
The following data is based on the
product
molecular weight
188.23
Batch specific molecular weights may vary
from batch to batch
due to the degree of hydration, which will
affect the solvent
volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass |
1 mg |
5 mg |
10 mg |
| 1 mM |
1.15 mL |
5.76 mL |
11.51 mL |
| 5 mM |
0.23 mL |
1.15 mL |
2.3 mL |
| 10 mM |
0.12 mL |
0.58 mL |
1.15 mL |
| 50 mM |
0.02 mL |
0.12 mL |
0.23 mL |
1: Woollard JM, Perry NB, Weavers RT, van Klink JW. Bullatenone, 1,3-dione and sesquiterpene chemotypes of Lophomyrtus species. Phytochemistry. 2008 Apr;69(6):1313-8. doi: 10.1016/j.phytochem.2008.01.016. Epub 2008 Mar 7. PMID: 18329059.
2: Larsen L, Benn MH, Parvez M, Perry NB. A cytotoxic triketone-phloroglucinol- bullatenone hybrid from Lophomyrtus bullata. Org Biomol Chem. 2005 Sep 7;3(17):3236-41. doi: 10.1039/b509076h. Epub 2005 Aug 3. PMID: 16106307.
3: Felman SW, Jirkovsky I, Memoli KA, Borella L, Wells C, Russell J, Ward J. Synthesis and antiulcer activity of novel 5-(2-ethenyl substituted)-3(2H)-furanones. J Med Chem. 1992 Apr 3;35(7):1183-90. doi: 10.1021/jm00085a003. PMID: 1560433.
4: Reiter M, Turner H, Mills-Webb R, Gouverneur V. Palladium-catalyzed oxidative cyclizations: synthesis of dihydropyranones and furanones. J Org Chem. 2005 Oct 14;70(21):8478-85. doi: 10.1021/jo051274d. PMID: 16209595.
5: Wilson RA, Chan L, Wood R, Brown RC. Synthesis and derivatisation of a novel spiro[1-benzofuran-2,4'-piperidin]-3-one scaffold. Org Biomol Chem. 2005 Sep 7;3(17):3228-35. doi: 10.1039/b507339a. Epub 2005 Aug 3. PMID: 16106306.
