|
Solvent |
mg/mL |
mM |
| Solubility |
| DMF |
25.0 |
41.47 |
| DMSO |
25.0 |
41.47 |
| Ethanol |
20.0 |
33.18 |
Note: There can be variations in solubility for the same chemical from different vendors or different batches from the same vendor. The following factors can affect the solubility of the same chemical: solvent used for crystallization, residual solvent content, polymorphism, salt versus free form, degree of hydration, solvent temperature. Please use the solubility data as a reference only. Warming and sonication will facilitate dissolving. Still have questions? Please contact our Technical Support scientists.
Preparing Stock Solutions
The following data is based on the
product
molecular weight
602.81
Batch specific molecular weights may vary
from batch to batch
due to the degree of hydration, which will
affect the solvent
volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass |
1 mg |
5 mg |
10 mg |
| 1 mM |
1.15 mL |
5.76 mL |
11.51 mL |
| 5 mM |
0.23 mL |
1.15 mL |
2.3 mL |
| 10 mM |
0.12 mL |
0.58 mL |
1.15 mL |
| 50 mM |
0.02 mL |
0.12 mL |
0.23 mL |
1: Cen J, Shi M, Yang Y, Fu Y, Zhou H, Wang M, Su Z, Wei Q. Isogarcinol is a new immunosuppressant. PLoS One. 2013 Jun 13;8(6):e66503. doi: 10.1371/journal.pone.0066503. PMID: 23785505; PMCID: PMC3681756.
2: Li W, Li H, Zhang M, Zhong Y, Wang M, Cen J, Wu H, Yang Y, Wei Q. Isogarcinol Extracted from Garcinia mangostana L. Ameliorates Systemic Lupus Erythematosus- like Disease in a Murine Model. J Agric Food Chem. 2015 Sep 30;63(38):8452-9. doi: 10.1021/acs.jafc.5b03425. Epub 2015 Sep 22. PMID: 26330173.
3: Wang M, Xie Y, Zhong Y, Cen J, Wang L, Liu Y, Zhu Y, Tong L, Wei Q. Amelioration of Experimental Autoimmune Encephalomyelitis by Isogarcinol Extracted from Garcinia mangostana L. Mangosteen. J Agric Food Chem. 2016 Nov 30;64(47):9012-9021. doi: 10.1021/acs.jafc.6b04145. Epub 2016 Nov 16. PMID: 27933873.
4: Chen S, Han K, Li H, Cen J, Yang Y, Wu H, Wei Q. Isogarcinol Extracted from Garcinia mangostana L. Ameliorates Imiquimod-Induced Psoriasis-like Skin Lesions in Mice. J Agric Food Chem. 2017 Feb 1;65(4):846-857. doi: 10.1021/acs.jafc.6b05207. Epub 2017 Jan 24. PMID: 28081600.
5: Fu Y, Zhou H, Wang M, Cen J, Wei Q. Immune regulation and anti-inflammatory effects of isogarcinol extracted from Garcinia mangostana L. against collagen- induced arthritis. J Agric Food Chem. 2014 May 7;62(18):4127-34. doi: 10.1021/jf405790q. Epub 2014 Apr 24. PMID: 24738849.
6: Cen J, Wang M, Jiang G, Yin Y, Su Z, Tong L, luo J, Ma Y, Gao Y, Wei Q. The new immunosuppressant, isogarcinol, binds directly to its target enzyme calcineurin, unlike cyclosporin A and tacrolimus. Biochimie. 2015 Apr;111:119-24. doi: 10.1016/j.biochi.2015.02.004. Epub 2015 Feb 17. PMID: 25701551.
