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MedKoo Cat#: 597100 | Name: Fellutamide A

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Fellutamide A is a tripeptide derivative from Penicillium fellutanum; enhances nerve growth factor (NGF) synthesis and secretion in vitro.

Chemical Structure

Fellutamide A
Fellutamide A
CAS#138682-08-3

Theoretical Analysis

MedKoo Cat#: 597100

Name: Fellutamide A

CAS#: 138682-08-3

Chemical Formula: C27H49N5O8

Exact Mass: 571.3581

Molecular Weight: 571.71

Elemental Analysis: C, 56.72; H, 8.64; N, 12.25; O, 22.39

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
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Synonym
Fellutamide A; (3-OH-1-Oxododecyl)asn-(3-OH)gln-leu-cho;
IUPAC/Chemical Name
(2S)-2-((S)-2,4-diamino-4-oxobutanamido)-3-hydroxy-N1-(3-hydroxydodecanoyl)-N1-((S)-4-methyl-1-oxopentan-2-yl)pentanediamide
InChi Key
XWNYAGCDJNGJCO-NCKDWAQUSA-N
InChi Code
InChI=1S/C27H49N5O8/c1-4-5-6-7-8-9-10-11-19(34)13-24(38)32(18(16-33)12-17(2)3)27(40)25(21(35)15-23(30)37)31-26(39)20(28)14-22(29)36/h16-21,25,34-35H,4-15,28H2,1-3H3,(H2,29,36)(H2,30,37)(H,31,39)/t18-,19?,20-,21?,25-/m0/s1
SMILES Code
CC(C)C[C@@H](C=O)N(C(CC(O)CCCCCCCCC)=O)C([C@H](C(O)CC(N)=O)NC([C@H](CC(N)=O)N)=O)=O
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 571.71 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Pirrung MC, Zhang F, Ambadi S, Gangadhara Rao Y. Total synthesis of fellutamides, lipopeptide proteasome inhibitors. More sustainable peptide bond formation. Org Biomol Chem. 2016 Sep 21;14(35):8367-75. doi: 10.1039/c6ob01233g. Epub 2016 Aug 17. PubMed PMID: 27533920; PubMed Central PMCID: PMC5303010. 2: Schneekloth JS Jr, Sanders JL, Hines J, Crews CM. Neurotrophic peptide aldehydes: solid phase synthesis of fellutamide B and a simplified analog. Bioorg Med Chem Lett. 2006 Jul 15;16(14):3855-8. Epub 2006 May 11. PubMed PMID: 16697191; PubMed Central PMCID: PMC2507734. 3: Yamaguchi K, Tsuji T, Wakuri S, Yazawa K, Kondo K, Shigemori H, Kobayashi J. Stimulation of nerve growth factor synthesis and secretion by fellutamide A in vitro. Biosci Biotechnol Biochem. 1993 Feb;57(2):195-9. PubMed PMID: 7763492.