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MedKoo Cat#: 145788 | Name: Murrangatin

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Murrangatin is a naturally occurring compound found in plants, particularly in species of the Murraya genus, such as Murraya koenigii, commonly known as curry leaves. It is a type of alkaloid and is studied for its potential biological activities. Some research suggests that murrangatin may have antimicrobial, antioxidant, and anti-inflammatory properties, although its full therapeutic potential is still under investigation. It is one of the compounds contributing to the medicinal properties attributed to plants in the Murraya genus, often used in traditional herbal medicine.

Chemical Structure

Murrangatin
Murrangatin
CAS#37126-91-3

Theoretical Analysis

MedKoo Cat#: 145788

Name: Murrangatin

CAS#: 37126-91-3

Chemical Formula: C15H16O5

Exact Mass: 276.1000

Molecular Weight: 276.29

Elemental Analysis: C, 65.21; H, 5.84; O, 28.95

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
Murrangatin;
IUPAC/Chemical Name
8-((1S,2R)-1,2-dihydroxy-3-methylbut-3-en-1-yl)-7-methoxy-2H-chromen-2-one
InChi Key
DKEANOQWICTXTP-KGLIPLIRSA-N
InChi Code
1S/C15H16O5/c1-8(2)13(17)14(18)12-10(19-3)6-4-9-5-7-11(16)20-15(9)12/h4-7,13-14,17-18H,1H2,2-3H3/t13-,14+/m1/s1
SMILES Code
COC1=CC=C2C=CC(=O)OC2=C1[C@H](O)[C@H](O)C(C)=C
Appearance
To be determined
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 -4 C for short term (days to weeks) or -20 C for long term(months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 276.29 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Long W, Wang M, Luo X, Huang G, Chen J. Murrangatin suppresses angiogenesis induced by tumor cell-derived media and inhibits AKT activation in zebrafish and endothelial cells. Drug Des Devel Ther. 2018 Sep 24;12:3107-3115. doi: 10.2147/DDDT.S145956. PMID: 30288018; PMCID: PMC6161741. 2: You CX, Yang K, Wang CF, Zhang WJ, Wang Y, Han J, Fan L, Du SS, Geng ZF, Deng ZW. Cytotoxic compounds isolated from Murraya tetramera Huang. Molecules. 2014 Aug 27;19(9):13225-34. doi: 10.3390/molecules190913225. PMID: 25165861; PMCID: PMC6271660. 3: Yu G, Zhang T, Xu H, Bi Y, Feng X, Wang J, Li T, Zhang C, Sun Y. Investigating the Active Substance and Mechanism of San-Jiu-Wei-Tai Granules via UPLC-QE-Orbitrap-MS and Network Pharmacology. Evid Based Complement Alternat Med. 2022 Oct 17;2022:1487903. doi: 10.1155/2022/1487903. PMID: 36299773; PMCID: PMC9592199. 4: Rodanant P, Khetkam P, Suksamrarn A, Kuvatanasuchati J. Coumarins and flavonoid from Murraya paniculata (L.) Jack: Antibacterial and anti-inflammation activity. Pak J Pharm Sci. 2015 Nov;28(6):1947-51. PMID: 26639491. 5: Saied S, Nizami SS, Anis I. Two new coumarins from Murraya paniculata. J Asian Nat Prod Res. 2008 May-Jun;10(5-6):515-9. doi: 10.1080/10286020801967292. PMID: 18470803. 6: Lekphrom R, Kanokmedhakul S, Kukongviriyapan V, Kanokmedhakul K. C-7 oxygenated coumarins from the fruits of Micromelum minutum. Arch Pharm Res. 2011 Apr;34(4):527-31. doi: 10.1007/s12272-011-0402-y. Epub 2011 May 5. PMID: 21544717. 7: Chen KS, Wu CC, Chang FR, Chia YC, Chiang MY, Wang WY, Wu YC. Bioactive coumarins from the leaves of Murraya omphalocarpa. Planta Med. 2003 Jul;69(7):654-7. doi: 10.1055/s-2003-41112. PMID: 12898423. 8: Negi N, Abou-Dough AM, Kurosawa M, Kitaji Y, Saito K, Ochi A, Ushijima K, Kusakabe E, Kitaguchi Y, Jinguji Y, Teshima N, Ju-ichi M, Ito C. Coumarins from Murraya exotica collected in Egypt. Nat Prod Commun. 2015 Apr;10(4):617-20. PMID: 25973490. 9: Teshima N, Yamada H, Ju-ichi M, Uji T, Kinoshita T, Ito C. Coumarins from Murraya paniculata var. zollingeri endemic to the Timor Islands. Nat Prod Commun. 2015 Feb;10(2):309-12. PMID: 25920269. 10: Arango V, Robledo S, Séon-Méniel B, Figadère B, Cardona W, Sáez J, Otálvaro F. Coumarins from Galipea panamensis and Their Activity against Leishmania panamensis. J Nat Prod. 2010 May 28;73(5):1012-4. doi: 10.1021/np100146y. PMID: 20423106. 11: Ito C, Itoigawa M, Furukawa H, Tokuda H, Okuda Y, Mukainaka T, Okuda M, Nishino H. Anti-tumor-promoting effects of 8-substituted 7-methoxycoumarins on Epstein-Barr virus activation assay. Cancer Lett. 1999 Apr 26;138(1-2):87-92. doi: 10.1016/s0304-3835(98)00376-0. PMID: 10378778.