AUT-00206 is an investigational compound developed as a positive modulator of Kv3.1 and Kv3.2 potassium channels. These channels are crucial for the proper functioning of GABAergic interneurons, which play a significant role in cognitive processes and neuronal excitability. By enhancing the activity of these channels, AUT-00206 aims to restore the balance of neuronal activity, potentially addressing cognitive and negative symptoms associated with schizophrenia. In preclinical studies, AUT-00206 has demonstrated the ability to normalize gamma oscillations and improve cognitive function in animal models.
MedKoo Cat#: 145770
Name: AUT-00206
CAS#: 1380696-64-9
Chemical Formula: C20H20N4O4
Exact Mass: 380.1500
Molecular Weight: 380.40
Elemental Analysis: C, 63.15; H, 5.30; N, 14.73; O, 16.82
The following data is based on the product molecular weight 380.40 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
