Lyso-Monosialoganglioside GM3 | Lyso-GM3 | It inhibits EGF-induced increases in EGFR kinase activity | CAS#94458-63-6

MedKoo Cat#: 128378 | Name: Lyso-Monosialoganglioside GM3

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Lyso-Monosialoganglioside GM3 (Lyso-GM3) is a form of ganglioside GM3 that is lacking the fatty acyl group.1 It inhibits EGF-induced increases in EGFR kinase activity in A431 epithelial cancer cells when used at a concentration of 500 µM. T

Chemical Structure

Lyso-Monosialoganglioside GM3

CAS#94458-63-6

Theoretical Analysis

MedKoo Cat#: 128378

Name: Lyso-Monosialoganglioside GM3

CAS#: 94458-63-6

Chemical Formula: C41H74N2O20

Exact Mass: 914.4835

Molecular Weight: 915.04

Elemental Analysis: C, 53.82; H, 8.15; N, 3.06; O, 34.97

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

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Related CAS #

No Data

Synonym

Lyso-Monosialoganglioside GM3; Lyso-GM3

IUPAC/Chemical Name

(2S,4S,5R,6R)-5-acetamido-2-(((2S,3R,4S,5S,6R)-2-(((2R,3S,4R,5R,6R)-6-(((2S,3R,E)-2-amino-3-hydroxyoctadec-4-en-1-yl)oxy)-4,5-dihydroxy-2-(hydroxymethyl)tetrahydro-2H-pyran-3-yl)oxy)-3,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-4-yl)oxy)-4-hydroxy-6-((1R,2R)-1,2,3-trihydroxypropyl)tetrahydro-2H-pyran-2-carboxylic acid

InChi Key

QLMGGRZACLACKO-PJSUIWAYSA-N

InChi Code

InChI=1S/C41H74N2O20/c1-3-4-5-6-7-8-9-10-11-12-13-14-15-16-24(48)23(42)21-58-38-33(54)32(53)35(28(20-46)60-38)61-39-34(55)37(31(52)27(19-45)59-39)63-41(40(56)57)17-25(49)29(43-22(2)47)36(62-41)30(51)26(50)18-44/h15-16,23-39,44-46,48-55H,3-14,17-21,42H2,1-2H3,(H,43,47)(H,56,57)/b16-15+/t23-,24+,25-,26+,27+,28+,29+,30+,31-,32+,33+,34+,35+,36+,37-,38+,39-,41-/m0/s1

SMILES Code

O[C@@H]([C@@H](O[C@H](CO)[C@H]1O[C@H]2[C@H](O)[C@@H](O[C@]3(O[C@@]([C@@H]([C@@H](O)C3)NC(C)=O)([H])[C@@H]([C@@H](CO)O)O)C(O)=O)[C@H]([C@H](O2)CO)O)OC[C@@H]([C@@H](/C=C/CCCCCCCCCCCCC)O)N)[C@H]1O

Appearance

To be determined

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 -4 C for short term (days to weeks) or -20 C for long term(months to years).

Solubility

To be determined

Shelf Life

>2 years if stored properly

Drug Formulation

To be determined

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 915.04 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.