GENZ-882706 | CAS#2070864-35-4 | CSF-1R inhibitor

MedKoo Cat#: 130460 | Name: GENZ-882706

Description:

WARNING: This product is for research use only, not for human or veterinary use.

GENZ-882706 is a CSF-1R inhibitor.

Chemical Structure

GENZ-882706

CAS#2070864-35-4

Theoretical Analysis

MedKoo Cat#: 130460

Name: GENZ-882706

CAS#: 2070864-35-4

Chemical Formula: C26H25N5O3

Exact Mass: 455.1957

Molecular Weight: 455.52

Elemental Analysis: C, 68.56; H, 5.53; N, 15.37; O, 10.54

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

Bulk Inquiry

Related CAS #

No Data

Synonym

GENZ-882706; GENZ882706; GENZ 882706; RA03546849; RA-03546849; RA 03546849

IUPAC/Chemical Name

(S)-4-(3-((2-(6-methoxypyridin-3-yl)-2,3-dihydrobenzo[b][1,4]dioxin-6-yl)methyl)-3H-imidazo[4,5-b]pyridin-6-yl)-2-methylbut-3-yn-2-amine

InChi Key

DRBFONOVLOXKJM-HSZRJFAPSA-N

InChi Code

InChI=1S/C26H25N5O3/c1-26(2,27)9-8-17-10-20-25(29-12-17)31(16-30-20)14-18-4-6-21-22(11-18)33-15-23(34-21)19-5-7-24(32-3)28-13-19/h4-7,10-13,16,23H,14-15,27H2,1-3H3/t23-/m1/s1

SMILES Code

CC(N)(C)C#CC1=CN=C(N(CC2=CC=C3O[C@@H](C4=CC=C(OC)N=C4)COC3=C2)C=N5)C5=C1

Appearance

To be determined

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

To be determined

Shelf Life

>2 years if stored properly

Drug Formulation

To be determined

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 455.52 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1. Hagan N, Kane JL, Grover D, Woodworth L, Madore C, Saleh J, Sancho J, Liu J, Li Y, Proto J, Zelic M, Mahan A, Kothe M, Scholte AA, Fitzgerald M, Gisevius B, Haghikia A, Butovsky O, Ofengeim D. CSF1R signaling is a regulator of pathogenesis in progressive MS. Cell Death Dis. 2020 Oct 23;11(10):904. doi: 10.1038/s41419-020-03084-7. PMID: 33097690; PMCID: PMC7584629.