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MedKoo Cat#: 145671 | Name: DM-4111

Description:

WARNING: This product is for research use only, not for human or veterinary use.

DM-4111 is a monohydroxylate.

Chemical Structure

DM-4111
DM-4111
CAS#926035-36-1

Theoretical Analysis

MedKoo Cat#: 145671

Name: DM-4111

CAS#: 926035-36-1

Chemical Formula: C26H25ClN2O4

Exact Mass: 464.1500

Molecular Weight: 464.95

Elemental Analysis: C, 67.17; H, 5.42; Cl, 7.62; N, 6.03; O, 13.76

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
DM-4111; DM4111; DM 4111;
IUPAC/Chemical Name
N-(4-((4S,5R)-7-chloro-4,5-dihydroxy-2,3,4,5-tetrahydro-1H-benzo[b]azepine-1-carbonyl)-3-methylphenyl)-2-methylbenzamide
InChi Key
VAVCSBDSVJMVNG-BJKOFHAPSA-N
InChi Code
1S/C26H25ClN2O4/c1-15-5-3-4-6-19(15)25(32)28-18-8-9-20(16(2)13-18)26(33)29-12-11-23(30)24(31)21-14-17(27)7-10-22(21)29/h3-10,13-14,23-24,30-31H,11-12H2,1-2H3,(H,28,32)/t23-,24+/m0/s1
SMILES Code
CC1=CC=CC=C1C(=O)NC2=CC(C)=C(C=C2)C(=O)N3CC[C@H](O)[C@H](O)C4=C3C=CC(Cl)=C4
Appearance
To be determined
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 -4 C for short term (days to weeks) or -20 C for long term(months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 464.95 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Hoshikawa K, Naito T, Saotome M, Maekawa Y, Kawakami J. Validated liquid chromatography coupled to tandem mass spectrometry method for simultaneous quantitation of tolvaptan and its five major metabolites in human plasma. Ann Clin Biochem. 2019 May;56(3):387-396. doi: 10.1177/0004563219827045. Epub 2019 Mar 4. PMID: 30832482. 2: Akutsu S, Mino Y, Naito T, Hoshikawa K, Saotome M, Maekawa Y, Kawakami J. Stereoselective interaction of tolvaptan with amiodarone under racemic metabolic impact by CYP3A5 genotypes in heart failure patients. Eur J Clin Pharmacol. 2022 Aug;78(8):1311-1320. doi: 10.1007/s00228-022-03341-y. Epub 2022 May 23. PMID: 35604424.