UNC6429 | MerTK inhibitor

MedKoo Cat#: 128075 | Name: UNC6429

Description:

WARNING: This product is for research use only, not for human or veterinary use.

UNC6429 is a MerTK inhibitor.

Chemical Structure

UNC6429

CAS#N/A

Theoretical Analysis

MedKoo Cat#: 128075

Name: UNC6429

CAS#: N/A

Chemical Formula: C25H33N5O

Exact Mass: 419.2685

Molecular Weight: 419.57

Elemental Analysis: C, 71.57; H, 7.93; N, 16.69; O, 3.81

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

Bulk Inquiry

Related CAS #

No Data

Synonym

UNC6429; UNC-6429; UNC 6429

IUPAC/Chemical Name

(1S,4r)-4-(2-(((S)-1-phenylethyl)amino)-5-(piperidin-4-yl)-7H-pyrrolo[2,3-d]pyrimidin-7-yl)cyclohexan-1-ol

InChi Key

WIPXVUIWCUCLDW-YYWHXJBOSA-N

InChi Code

InChI=1S/C25H33N5O/c1-17(18-5-3-2-4-6-18)28-25-27-15-22-23(19-11-13-26-14-12-19)16-30(24(22)29-25)20-7-9-21(31)10-8-20/h2-6,15-17,19-21,26,31H,7-14H2,1H3,(H,27,28,29)/t17-,20-,21-/m0/s1

SMILES Code

C[C@@H](C1=CC=CC=C1)NC2=NC=C3C(C4CCNCC4)=CN([C@@H]5CC[C@@H](O)CC5)C3=N2

Appearance

To be determined

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 -4 C for short term (days to weeks) or -20 C for long term(months to years).

Solubility

To be determined

Shelf Life

>2 years if stored properly

Drug Formulation

To be determined

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 419.57 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

Wong SW, Vivash L, Mudududdla R, Nguyen N, Hermans SJ, Shackleford DM, Field J, Xue L, Aprico A, Hancock NC, Haskali M, Stashko MA, Frye SV, Wang X, Binder MD, Ackermann U, Parker MW, Kilpatrick TJ, Baell JB. Development of [18F]MIPS15692, a radiotracer with in vitro proof-of-concept for the imaging of MER tyrosine kinase (MERTK) in neuroinflammatory disease. Eur J Med Chem. 2021 Dec 15;226:113822. doi: 10.1016/j.ejmech.2021.113822. Epub 2021 Sep 4. PMID: 34563964.