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MedKoo Cat#: 127973 | Name: SPAA-52 NH4

Description:

WARNING: This product is for research use only, not for human or veterinary use.

SPAA-52 is a LMW-PTP inhibitor (Ki = 1.2 nM, >8000-fold selectivity).

Chemical Structure

SPAA-52 NH4
SPAA-52 NH4
CAS#SPAA-52 NH4

Theoretical Analysis

MedKoo Cat#: 127973

Name: SPAA-52 NH4

CAS#: SPAA-52 NH4

Chemical Formula: C8H11Br2N3O4S

Exact Mass: 0.0000

Molecular Weight: 405.06

Elemental Analysis: C, 23.72; H, 2.74; Br, 39.45; N, 10.37; O, 15.80; S, 7.91

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
SPAA-52 SPAA-52 NH4
Synonym
SPAA-52; SPAA52; SPAA 52; SPAA-52 NH4
IUPAC/Chemical Name
ammonium ((3,5-dibromo-4-methylphenyl)carbamoyl)sulfamate
InChi Key
RMSNSCWKISLJSQ-UHFFFAOYSA-N
InChi Code
InChI=1S/C8H8Br2N2O4S.H3N/c1-4-6(9)2-5(3-7(4)10)11-8(13)12-17(14,15)16;/h2-3H,1H3,(H2,11,12,13)(H,14,15,16);1H3
SMILES Code
[O-]S(=O)(NC(NC(C=C1Br)=CC(Br)=C1C)=O)=O.[NH4+]
Appearance
To be determined
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 -4 C for short term (days to weeks) or -20 C for long term(months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 405.06 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1. He R, Wang J, Yu ZH, Moyers JS, Michael MD, Durham TB, Cramer JW, Qian Y, Lin A, Wu L, Noinaj N, Barrett DG, Zhang ZY. Structure-Based Design of Active-Site-Directed, Highly Potent, Selective, and Orally Bioavailable Low-Molecular-Weight Protein Tyrosine Phosphatase Inhibitors. J Med Chem. 2022 Oct 27;65(20):13892-13909. doi: 10.1021/acs.jmedchem.2c01143. Epub 2022 Oct 5. PMID: 36197449.