Pterulone | CAS#369376-61-4 | antibiotic

MedKoo Cat#: 145365 | Name: Pterulone

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Pterulone is a novel halogenated antibiotics. Pterulone is isolated from fermentations of Pterula sp. 82168. Pterulone contains a 1-benzoxepin ring system and is chlorinated.

Chemical Structure

Pterulone

CAS#369376-61-4

Theoretical Analysis

MedKoo Cat#: 145365

Name: Pterulone

CAS#: 369376-61-4

Chemical Formula: C13H11ClO2

Exact Mass: 234.0448

Molecular Weight: 234.68

Elemental Analysis: C, 66.53; H, 4.72; Cl, 15.11; O, 13.63

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

Bulk Inquiry

Related CAS #

No Data

Synonym

Pterulone;

IUPAC/Chemical Name

(Z)-1-(3-(chloromethylene)-2,3-dihydrobenzo[b]oxepin-7-yl)ethan-1-one

InChi Key

QEWSARCWWQPUSM-YFHOEESVSA-N

InChi Code

1S/C13H11ClO2/c1-9(15)11-4-5-13-12(6-11)3-2-10(7-14)8-16-13/h2-7H,8H2,1H3/b10-7-

SMILES Code

CC(=O)C1=CC=C2OC\C(=C/Cl)C=CC2=C1

Appearance

To be determined

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 -4 C for short term (days to weeks) or -20 C for long term(months to years).

Solubility

To be determined

Shelf Life

>2 years if stored properly

Drug Formulation

To be determined

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 234.68 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Lemaire P, Balme G, Desbordes P, Vors JP. Efficient syntheses of pterulone, pterulone B and related analogues. Org Biomol Chem. 2003 Dec 7;1(23):4209-19. doi: 10.1039/b306356a. Epub 2003 Oct 23. PMID: 14685322. 2: Engler M, Anke T, Sterner O, Brandt U. Pterulinic acid and pterulone, two novel inhibitors of NADH:ubiquinone oxidoreductase (complex I) produced by a Pterula species. I. Production, isolation and biological activities. J Antibiot (Tokyo). 1997 Apr;50(4):325-9. doi: 10.7164/antibiotics.50.325. PMID: 9186558. 3: Engler M, Anke T, Sterner O. Pterulinic acid and pterulone, two novel inhibitors of NADH:ubiquinone oxidoreductase (complex I) produced by a Pterula species. II. Physico-chemical properties and structure elucidation. J Antibiot (Tokyo). 1997 Apr;50(4):330-3. doi: 10.7164/antibiotics.50.330. PMID: 9186559. 4: Engler M, Anke T, Sterner O. Production of antibiotics by Collybia nivalis, Omphalotus olearis, a Favolaschia and a Pterula species on natural substrates. Z Naturforsch C J Biosci. 1998 May-Jun;53(5-6):318-24. doi: 10.1515/znc-1998-5-604. PMID: 9705612.