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MedKoo Cat#: 161001 | Name: NOTHOAPIOLE

Description:

WARNING: This product is for research use only, not for human or veterinary use.

NOTHOAPIOLE is an antibacterial and antifungal agent. NOTHOAPIOLE is a chemical constituent of the essential oil and oleoresin of the seed from Carum nigrum.

Chemical Structure

NOTHOAPIOLE
NOTHOAPIOLE
CAS#22934-74-3

Theoretical Analysis

MedKoo Cat#: 161001

Name: NOTHOAPIOLE

CAS#: 22934-74-3

Chemical Formula: C13H16O5

Exact Mass: 252.1000

Molecular Weight: 252.27

Elemental Analysis: C, 61.90; H, 6.39; O, 31.71

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
NOTHOAPIOLE; RADIATININ;
IUPAC/Chemical Name
5-allyl-4,6,7-trimethoxybenzo[d][1,3]dioxole
InChi Key
IWGPXDGGZYMDJF-UHFFFAOYSA-N
InChi Code
1S/C13H16O5/c1-5-6-8-9(14-2)11(16-4)13-12(10(8)15-3)17-7-18-13/h5H,1,6-7H2,2-4H3
SMILES Code
COC1=C2OCOC2=C(OC)C(OC)=C1CC=C
Appearance
To be determined
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 -4 C for short term (days to weeks) or -20 C for long term(months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 252.27 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Baba M, Ito M. Cloning of the cytochrome P450 enzyme from Perilla frutescens involved in nothoapiole biosynthesis. J Nat Med. 2021 Jun;75(3):577-589. doi: 10.1007/s11418-021-01503-3. Epub 2021 Mar 29. PMID: 33779945. 2: Laouer H, Meriem el K, Prado S, Baldovini N. An antibacterial and antifungal phenylpropanoid from Carum montanum (Coss. et Dur.) Benth. et Hook. Phytother Res. 2009 Dec;23(12):1726-30. doi: 10.1002/ptr.2820. PMID: 19370550. 3: Singh G, Marimuthu P, de Heluani CS, Catalan CA. Antioxidant and biocidal activities of Carum nigrum (seed) essential oil, oleoresin, and their selected components. J Agric Food Chem. 2006 Jan 11;54(1):174-81. doi: 10.1021/jf0518610. PMID: 16390196. 4: Lim HJ, Woo KW, Lee KR, Lee SK, Kim HP. Inhibition of Proinflammatory Cytokine Generation in Lung Inflammation by the Leaves of Perilla frutescens and Its Constituents. Biomol Ther (Seoul). 2014 Jan;22(1):62-7. doi: 10.4062/biomolther.2013.088. PMID: 24596623; PMCID: PMC3936423. 5: Kapoor IP, Singh B, Singh G, De Heluani CS, De Lampasona MP, Catalan CA. Chemistry and antioxidant activity of essential oil and oleoresins of black caraway (Carum bulbocastanum) fruits: Part 69. J Sci Food Agric. 2010 Feb;90(3):385-90. doi: 10.1002/jsfa.3824. PMID: 20355057.