MedKoo Biosciences, Inc.
Tel:   +1-919-636-5577    Fax:   +1-919-980-4831    Email:   sales@medkoo.com
Search
Login Register
Search
MedKoo Cat#: 150123 | Name: 16,16-dimethylprostaglandin E2
Featured

Description:

WARNING: This product is for research use only, not for human or veterinary use.

16,16-dimethyl Prostaglandin E2 acts as an agonist on most prostaglandin E (EP) receptor subtypes.

Chemical Structure

16,16-dimethylprostaglandin E2
16,16-dimethylprostaglandin E2
CAS#39746-25-3

Theoretical Analysis

MedKoo Cat#: 150123

Name: 16,16-dimethylprostaglandin E2

CAS#: 39746-25-3

Chemical Formula: C22H36O5

Exact Mass: 380.2560

Molecular Weight: 380.53

Elemental Analysis: C, 69.44; H, 9.54; O, 21.02

Price and Availability

Size Price Availability Quantity
1mg USD 350.00 2 Weeks
Bulk Inquiry
Buy Now
Add to Cart
Related CAS #
No Data
Synonym
16,16-dimethyl prostaglandin E2; 16,16-Dimethyl-pge2; 16,16-dimethylprostaglandin E2; 16,16-Dimethyl-prostaglandin E2;
IUPAC/Chemical Name
(Z)-7-[(1R,2R,3R)-3-hydroxy-2-[(E,3R)-3-hydroxy-4,4-dimethyloct-1-enyl]-5-oxocyclopentyl]hept-5-enoic acid
InChi Key
QAOBBBBDJSWHMU-WMBBNPMCSA-N
InChi Code
1S/C22H36O5/c1-4-5-14-22(2,3)20(25)13-12-17-16(18(23)15-19(17)24)10-8-6-7-9-11-21(26)27/h6,8,12-13,16-17,19-20,24-25H,4-5,7,9-11,14-15H2,1-3H3,(H,26,27)/b8-6-,13-12+/t16-,17-,19-,20-/m1/s1
SMILES Code
O=C(O)CCC/C=C\C[C@@H]1[C@@H](/C=C/[C@@H](O)C(C)(C)CCCC)[C@H](O)CC1=O
Appearance
A solution in methyl acetate
Purity
>95% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 -4 C for short term (days to weeks) or -20 C for long term(months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 380.53 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1. Cutler C, Multani P, Robbins D, et al. Prostaglandin-modulated umbilical cord blood hematopoietic stem cell transplantation. Blood. 2013 Oct;122(17):3074-3081. DOI: 10.1182/blood-2013-05-503177. PMID: 23996087; PMCID: PMC3811179. 2. Failla M, Genovese T, Mazzon E, et al. 16,16-Dimethyl prostaglandin E2 efficacy on prevention and protection from bleomycin-induced lung injury and fibrosis. American Journal of Respiratory Cell and Molecular Biology. 2009 Jul;41(1):50-58. DOI: 10.1165/rcmb.2007-0438oc. PMID: 19059888. 3. Kunikata T, Tanaka A, Miyazawa T, Kato S, Takeuchi K. 16,16-Dimethyl prostaglandin E2 inhibits indomethacin-induced small intestinal lesions through EP3 and EP4 receptors. Digestive Diseases and Sciences. 2002 Apr;47(4):894-904. DOI: 10.1023/a:1014725024519. PMID: 11991626.