ASP-2205 is a novel 5-HT2C receptor agonist. ASP2205 can enhance the pudendal nerve-mediated urethral closure reflex via the 5-HT2C receptor, resulting in the prevention of involuntary urine loss. ASP2205, a serotonin 5-HT2c receptor agonist, does not increase the urethral pressure and is unlikely to be used as a treatment for stress urinary incontinence. ASP2205 is less well tolerated than the high dose of duloxetine.
MedKoo Cat#: 145297
Name: ASP-2205
CAS#: 1334440-09-3
Chemical Formula: C19H28N2O
Exact Mass: 300.2202
Molecular Weight: 300.45
Elemental Analysis: C, 75.96; H, 9.39; N, 9.32; O, 5.33
The following data is based on the product molecular weight 300.45 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
