Anisperimus, also known as LF 15-0195, is an analogue of 15-deoxyspergualin and an immunosuppressive agent. LF 15-0195 treatment protects against central nervous system autoimmunity by favoring the development of Foxp3-expressing regulatory CD4 T cells. LF 15-0195 generates synergistic tolerance by promoting formation of CD4+CD25+CTLA4+ T cells. Monotherapy with LF 15-0195 significantly prolongs renal allograft survival in monkeys.
MedKoo Cat#: 127436
Name: Anisperimus
CAS#: 170368-04-4 (free base)
Chemical Formula: C18H39N7O3
Exact Mass: 401.3114
Molecular Weight: 401.56
Elemental Analysis: C, 53.84; H, 9.79; N, 24.42; O, 11.95
The following data is based on the product molecular weight 401.56 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
