FR-145715 is a novel histamine H2 receptor antagonist. FR145715 antagonizes the effect of histamine on heart rate with approximately three times more potent activity than ranitidine. FR145715 might be useful for patients suffering from ulcer relapse, since the drug might be able to eradicate H. pylori in the stomach, which is considered a key factor to cause ulcer recurrence in humans.
MedKoo Cat#: 145241
Name: FR-145715
CAS#: 149917-31-7
Chemical Formula: C16H21N5O2S
Exact Mass: 347.1416
Molecular Weight: 347.44
Elemental Analysis: C, 55.31; H, 6.09; N, 20.16; O, 9.21; S, 9.23
The following data is based on the product molecular weight 347.44 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
