LY 221068 | CAS#132392-39-3

MedKoo Cat#: 525519 | Name: LY 221068

Description:

WARNING: This product is for research use only, not for human or veterinary use.

LY 221068 is a potent antioxidant with antiinflammatory properties.

Chemical Structure

LY 221068

CAS#132392-39-3

Theoretical Analysis

MedKoo Cat#: 525519

Name: LY 221068

CAS#: 132392-39-3

Chemical Formula: C20H30N2O2S

Exact Mass: 362.2028

Molecular Weight: 362.53

Elemental Analysis: C, 66.26; H, 8.34; N, 7.73; O, 8.83; S, 8.84

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

Bulk Inquiry

Related CAS #

No Data

Synonym

LY 221068; LY-221068; LY221068.

IUPAC/Chemical Name

5-((3,5-Bis(1,1,-dimethylethyl)-4-hydroxyphenyl)methylene)-3-(dimethylamino)-4-thiazolidinone

InChi Key

DNXBQWAKVPAADQ-WJDWOHSUSA-N

InChi Code

InChI=1S/C20H30N2O2S/c1-19(2,3)14-9-13(10-15(17(14)23)20(4,5)6)11-16-18(24)22(12-25-16)21(7)8/h9-11,23H,12H2,1-8H3/b16-11-

SMILES Code

S1CN(C(\C1=C\c1cc(c(c(c1)C(C)(C)C)O)C(C)(C)C)=O)N(C)C

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>2 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 362.53 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Chandrasekhar S, Panetta JA, Bendele AM. Inhibition of IL-1 induced articular inflammation of rats by 4-aminothiazolidines, LY 221068 and LY 269415. Agents Actions. 1994 Aug;42(1-2):67-70. PubMed PMID: 7847188. 2: Panetta JA, Shadle JK, Phillips ML, Benslay DN, Ho PP. 4-Thiazolidinones, potent antioxidants, as antiinflammatory agents. Ann N Y Acad Sci. 1993 Nov 30;696:415-6. PubMed PMID: 8109854. 3: Panetta JA, Benslay DN, Shadle JK, Towner RD, Ho PP. Anti-inflammatory effects of LY221068 and LY269415. Agents Actions. 1991 Sep;34(1-2):100-2. PubMed PMID: 1793009.