Rpi 856 A | CAS#157381-54-9 | retrovirus protease inhibitor

MedKoo Cat#: 596907 | Name: Rpi 856 A

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Rpi 856 A is a retrovirus protease inhibitor isolated from Streptomyces; effective against HIV-1 and HTLV-1 proteases.

Chemical Structure

Rpi 856 A

CAS#157381-54-9

Theoretical Analysis

MedKoo Cat#: 596907

Name: Rpi 856 A

CAS#: 157381-54-9

Chemical Formula: C43H61N7O13

Exact Mass: 883.4327

Molecular Weight: 883.99

Elemental Analysis: C, 58.42; H, 6.96; N, 11.09; O, 23.53

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

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Related CAS #

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Synonym

Rpi 856 A; Rpi-856 A; Rpi856 A; Rpi 856 B; Rpi-856 B; Rpi856 B;

IUPAC/Chemical Name

N-(3-amino-2-oxo-4-phenylbutanoyl)-N-((2-((S)-2-amino-3-methylbutanamido)-2-(3,5-dihydroxyphenyl)acetyl)-L-leucyl)-L-valyl-L-valyl-L-aspartic acid

InChi Key

JEQXCALAKRMZJH-AIWBLNLQSA-N

InChi Code

InChI=1S/C43H61N7O13/c1-20(2)14-29(46-39(58)34(49-37(56)32(45)21(3)4)25-16-26(51)18-27(52)17-25)41(60)50(42(61)36(55)28(44)15-24-12-10-9-11-13-24)35(23(7)8)40(59)48-33(22(5)6)38(57)47-30(43(62)63)19-31(53)54/h9-13,16-18,20-23,28-30,32-35,51-52H,14-15,19,44-45H2,1-8H3,(H,46,58)(H,47,57)(H,48,59)(H,49,56)(H,53,54)(H,62,63)/t28?,29-,30-,32-,33-,34?,35-/m0/s1

SMILES Code

O=C(O)C[C@@H](C(O)=O)NC([C@H](C(C)C)NC([C@H](C(C)C)N(C([C@H](CC(C)C)NC(C(C1=CC(O)=CC(O)=C1)NC([C@H](C(C)C)N)=O)=O)=O)C(C(C(N)CC2=CC=CC=C2)=O)=O)=O)=O

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>2 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 883.99 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Kitazaki T, Asano T, Kato K, Kishimoto S, Itoh K. Synthesis and human immunodeficiency virus (HIV)-1 protease inhibitory activity of tripeptide analogues containing a dioxoethylene moiety. Chem Pharm Bull (Tokyo). 1994 Dec;42(12):2636-40. PubMed PMID: 7697778. 2: Asano T, Matsuoka K, Hida T, Kobayashi M, Kitamura Y, Hayakawa T, Iinuma S, Kakinuma A, Kato K. Novel retrovirus protease inhibitors, RPI-856 A, B, C and D, produced by Streptomyces sp. AL-322. J Antibiot (Tokyo). 1994 May;47(5):557-65. PubMed PMID: 8040053.