BE-12406B | CAS#132417-97-1 | antitumor substance

MedKoo Cat#: 145218 | Name: BE-12406B

Description:

WARNING: This product is for research use only, not for human or veterinary use.

BE-12406B is an antitumor substance. BE-12406B inhibits the growth of vincristine-resistant or doxorubicin-resistant P388 murine leukemia cell lines.

Chemical Structure

BE-12406B

CAS#132417-97-1

Theoretical Analysis

MedKoo Cat#: 145218

Name: BE-12406B

CAS#: 132417-97-1

Chemical Formula: C24H22O9

Exact Mass: 454.1264

Molecular Weight: 454.43

Elemental Analysis: C, 63.43; H, 4.88; O, 31.69

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

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Related CAS #

No Data

Synonym

BE-12406B; BE12406B; BE 12406B;

IUPAC/Chemical Name

1,10-dihydroxy-8-methyl-12-(((2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-6H-dibenzo[c,h]chromen-6-one

InChi Key

ZGDUJABECFPJCG-NYPUNPOJSA-N

InChi Code

1S/C24H22O9/c1-9-6-13-17(15(26)7-9)12-8-16(32-24-21(29)20(28)19(27)10(2)31-24)18-11(4-3-5-14(18)25)22(12)33-23(13)30/h3-8,10,19-21,24-29H,1-2H3/t10-,19-,20+,21+,24-/m0/s1

SMILES Code

C[C@@H]1O[C@@H](OC2=C3C(O)=CC=CC3=C4OC(=O)C5=CC(C)=CC(O)=C5C4=C2)[C@H](O)[C@H](O)[C@H]1O

Appearance

To be determined

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 -4 C for short term (days to weeks) or -20 C for long term(months to years).

Solubility

To be determined

Shelf Life

>2 years if stored properly

Drug Formulation

To be determined

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 454.43 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Kojiri K, Arakawa H, Satoh F, Kawamura K, Okura A, Suda H, Okanishi M. New antitumor substances, BE-12406A and BE-12406B, produced by a streptomycete. I. Taxonomy, fermentation, isolation, physico-chemical and biological properties. J Antibiot (Tokyo). 1991 Oct;44(10):1054-60. doi: 10.7164/antibiotics.44.1054. PMID: 1955386. 2: Nakajima S, Kojiri K, Suda H, Okanishi M. New antitumor substances, BE-12406A and BE-12406B, produced by a streptomycete. II. Structure determination. J Antibiot (Tokyo). 1991 Oct;44(10):1061-4. doi: 10.7164/antibiotics.44.1061. PMID: 1955387.