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MedKoo Cat#: 127279 | Name: Elzasonan HCl

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Elzasonan (CP 448187) is a serotonin 1B/1D receptor antagonist.

Chemical Structure

Elzasonan HCl
Elzasonan HCl
CAS#220322-05-4 (HCl)

Theoretical Analysis

MedKoo Cat#: 127279

Name: Elzasonan HCl

CAS#: 220322-05-4 (HCl)

Chemical Formula: C22H24Cl3N3OS

Exact Mass: 483.0706

Molecular Weight: 484.86

Elemental Analysis: C, 54.50; H, 4.99; Cl, 21.93; N, 8.67; O, 3.30; S, 6.61

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
361343-19-3 (free base) 220322-05-4 (HCl) 361343-20-6 (Citrate)
Synonym
Elzasonan; CP 448187; CP-448187; CP448187; Elzasonan HCl; Elzasonan hydrochloride
IUPAC/Chemical Name
(Z)-4-(3,4-dichlorophenyl)-2-(2-(4-methylpiperazin-1-yl)benzylidene)thiomorpholin-3-one hydrochloride
InChi Key
NMTRXBJYASHMND-UXTSPRGOSA-N
InChi Code
InChI=1S/C22H23Cl2N3OS.ClH/c1-25-8-10-26(11-9-25)20-5-3-2-4-16(20)14-21-22(28)27(12-13-29-21)17-6-7-18(23)19(24)15-17;/h2-7,14-15H,8-13H2,1H3;1H/b21-14-;
SMILES Code
Cl.CN1CCN(CC1)C2=CC=CC=C2\C=C3/SCCN(C3=O)C4=CC=C(Cl)C(Cl)=C4
Appearance
To be determined
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 -4 C for short term (days to weeks) or -20 C for long term(months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 484.86 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Kamel A, Colizza K, Obach RS. In vitro metabolism of the 5-hydroxytryptamine1B receptor antagonist elzasonan. Xenobiotica. 2013 Apr;43(4):368-78. doi: 10.3109/00498254.2012.723150. Epub 2012 Oct 3. PubMed PMID: 23030680. 2: Kamel A, Obach RS, Colizza K, Wang W, O'Connell TN, Coelho RV Jr, Kelley RM, Schildknegt K. Metabolism, pharmacokinetics, and excretion of the 5-hydroxytryptamine1b receptor antagonist elzasonan in humans. Drug Metab Dispos. 2010 Nov;38(11):1984-99. doi: 10.1124/dmd.110.034595. Epub 2010 Jul 28. PubMed PMID: 20668248.