IUPAC/Chemical Name
(R)-3-(difluoromethyl)-1-methyl-N-(1,1,3-trimethyl-2,3-dihydro-1H-inden-4-yl)-1H-pyrazole-4-carboxamide
InChi Key
YTCIYOXHHQLDEI-SNVBAGLBSA-N
InChi Code
1S/C18H21F2N3O/c1-10-8-18(2,3)12-6-5-7-13(14(10)12)21-17(24)11-9-23(4)22-15(11)16(19)20/h5-7,9-10,16H,8H2,1-4H3,(H,21,24)/t10-/m1/s1
SMILES Code
C[C@@H]1CC(C)(C)C2=CC=CC(NC(=O)C3=CN(C)N=C3C(F)F)=C12
Appearance
To be determined
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 -4 C for short term (days to weeks) or -20 C for long term(months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
Preparing Stock Solutions
The following data is based on the
product
molecular weight
333.38
Batch specific molecular weights may vary
from batch to batch
due to the degree of hydration, which will
affect the solvent
volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass |
1 mg |
5 mg |
10 mg |
| 1 mM |
1.15 mL |
5.76 mL |
11.51 mL |
| 5 mM |
0.23 mL |
1.15 mL |
2.3 mL |
| 10 mM |
0.12 mL |
0.58 mL |
1.15 mL |
| 50 mM |
0.02 mL |
0.12 mL |
0.23 mL |
1: Irie Y, Nakae H. Warning about use of pesticides containing inpyrfluxam for suicide. Acute Med Surg. 2023 Mar 14;10(1):e834. doi: 10.1002/ams2.834. PMID: 36936739; PMCID: PMC10014421.
2: Adachi T, Suzuki Y, Fujisawa T. Photodegradation of an Anilide Fungicide Inpyrfluxam in Water and Nitrate Aqueous Solution. J Agric Food Chem. 2021 Nov 10;69(44):12966-12973. doi: 10.1021/acs.jafc.1c03813. Epub 2021 Oct 26. PMID: 34699205.
3: Ayer KM, Villani SM, Choi MW, Cox KD. Characterization of the VisdhC and VisdhD Genes in Venturia inaequalis, and Sensitivity to Fluxapyroxad, Pydiflumetofen, Inpyrfluxam, and Benzovindiflupyr. Plant Dis. 2019 Jun;103(6):1092-1100. doi: 10.1094/PDIS-07-18-1225-RE. Epub 2019 Apr 22. PMID: 31012823.
4: Peng J, Sang H, Proffer TJ, Gleason J, Outwater CA, Jung G, Sundin GW. A Method for the Examination of SDHI Fungicide Resistance Mechanisms in Phytopathogenic Fungi Using a Heterologous Expression System in Sclerotinia sclerotiorum. Phytopathology. 2021 May;111(5):819-830. doi: 10.1094/PHYTO-09-20-0421-R. Epub 2021 Apr 14. PMID: 33141650.
5: Matsuzaki Y, Harada T, Iwahashi F. In vitro and in planta investigation of succinate dehydrogenase inhibitor resistance conferred by target-site amino acid substitutions in Puccinia horiana, chrysanthemum white rust. Pest Manag Sci. 2024 Jun;80(6):2874-2880. doi: 10.1002/ps.7995. Epub 2024 Feb 12. PMID: 38345375.
6: Cosseboom SD, Hu M. Identification and Characterization of Fungicide Resistance in Botrytis Populations from Small Fruit Fields in the Mid-Atlantic United States. Plant Dis. 2021 Mar 9. doi: 10.1094/PDIS-03-20-0487-RE. Epub ahead of print. PMID: 33719541.
7: Martin PL, Krawczyk T, Pierce K, Thomas C, Khodadadi F, Aćimović SG, Peter KA. Fungicide Sensitivity of Colletotrichum Species Causing Bitter Rot of Apple in the Mid-Atlantic U.S.A. Plant Dis. 2022 Feb;106(2):549-563. doi: 10.1094/PDIS-06-21-1142-RE. Epub 2022 Feb 8. PMID: 34353127.
