VR17-04 is a metabolite of Enisamium. VR17-04 prevents the incorporation of GTP and UTP during RNA synthesis. Docking and molecular dynamics simulations provide mechanistic insights into its action. These findings suggest VR17-04 as a potential antiviral strategy for managing COVID-19.
MedKoo Cat#: 145068
Name: VR17-04
CAS#: 2417925-64-3
Chemical Formula: C14H15N2O2+
Exact Mass: 243.1128
Molecular Weight: 243.29
Elemental Analysis: C, 69.12; H, 6.21; N, 11.51; O, 13.15
The following data is based on the product molecular weight 243.29 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
