MedKoo Cat#: 127921 | Name: BC-​1258
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

BC-1258, an F-box/LRR-repeat protein 2 (FBXL2) activator, can stabilize and upregulate FBXL2 levels.

Chemical Structure

BC-​1258
BC-​1258
CAS#1507370-40-2

Theoretical Analysis

MedKoo Cat#: 127921

Name: BC-​1258

CAS#: 1507370-40-2

Chemical Formula: C22H22N4S2

Exact Mass: 406.1286

Molecular Weight: 406.57

Elemental Analysis: C, 64.99; H, 5.45; N, 13.78; S, 15.77

Price and Availability

Size Price Availability Quantity
25mg USD 350.00 2 Weeks
50mg USD 550.00 2 Weeks
100mg USD 950.00 2 Weeks
1g USD 4,250.00 2 Weeks
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Related CAS #
No Data
Synonym
BC-​1258; BC 1258; BC​1258
IUPAC/Chemical Name
N1,N2-bis(4-(thiazol-2-yl)benzyl)ethane-1,2-diamine
InChi Key
FRTSLZJCGAFSET-UHFFFAOYSA-N
InChi Code
InChI=1S/C22H22N4S2/c1-5-19(21-25-11-13-27-21)6-2-17(1)15-23-9-10-24-16-18-3-7-20(8-4-18)22-26-12-14-28-22/h1-8,11-14,23-24H,9-10,15-16H2
SMILES Code
C1(CNCCNCC2=CC=C(C3=NC=CS3)C=C2)=CC=C(C4=NC=CS4)C=C1
Appearance
To be determined
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 -4 C for short term (days to weeks) or -20 C for long term(months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 406.57 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Chen BB, Glasser JR, Coon TA, Mallampalli RK. Skp-cullin-F box E3 ligase component FBXL2 ubiquitinates Aurora B to inhibit tumorigenesis. Cell Death Dis. 2013 Aug 8;4(8):e759. doi: 10.1038/cddis.2013.271. PMID: 23928698; PMCID: PMC3763433.